Clinical characteristics of ocular toxocariasis in Eastern China

Min Zhou, Qing Chang, John A. Gonzales, Qian Chen, Yanqiong Zhang, Xin Huang, Gezhi Xu, Wenji Wang, Rui Jiang

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


Purpose To explore the clinical characteristics of patients with ocular toxocariasis in eastern China. Methods The medical records of 35 cases of ocular toxocariasis in Fudan University Eye & ENT Hospital between May 2009 and April 2011 were retrospectively reviewed and analyzed. UBM, RetCam or fundus imaging, and highfrequency or conventional ultrasonography were performed in these patients. Results The mean patient age in our series of ocular toxocariasis was 11.86±8.80 years. There were 28 children and seven adults, the majority residing in a rural area (88.57%). All cases were classified into three clinical subtypes: granuloma in the peripheral retina (60% of cases); granuloma in the posterior pole (28.57% of cases); and vitreous inflammation mimicking chronic endophthalmitis (5.71% of cases). We also identified an additional subtype with unique clinical features that we termed "combined type" presenting in 5.71% of our patients. This subtype exhibited granulomas in both the posterior pole and peripheral retina. RetCam fundus imaging was able to identify granulomas in the posterior and peripheral subtypes, 100% and 80.95% of cases respectively. Moreover, UBM combined with conventional ultrasonography identified granulomas in 95% of the peripheral subtype cases and in 100% of the posterior pole subtype cases. Conclusions This is the first ocular toxocariasis series described in Chinese patients. Compared with reports from developed countries, the ocular features in our series were more severe and complicated, presenting with poorer visual acuity and a high rate of retinal detachment (45.7%). The application of RetCam and UBM during examination in ocular toxocariasis can provide valuable information in determining the severity of disease and features important in considering surgical procedures in such patients.

Original languageEnglish (US)
Pages (from-to)1373-1378
Number of pages6
JournalGraefe's Archive for Clinical and Experimental Ophthalmology
Issue number9
StatePublished - Sep 2012


  • Ocular toxocariasis
  • Retcam imaging
  • Ultrasound biomicroscopic imaging

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience


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