Abstract
The effect of lipid-based parenteral nutrition was assessed in eight patients with AIDS and weight loss of 10% or greater. All patients received home parenteral nutrition consisting of a lipid-based system with 50% of nonprotein calories given as fat. Measurements were made of body weight, serum albumin, and immune function as assessed by mitogen responses, P24 antigen levels and T-cell counts. Over a period of 2 months, weight gain and improved well-being were noted in all patients. An improved in vitro lymphocyte mitogenic response to phytohemagglutinin and to concanavalin A was also noted. No change in T-cell subsets was observed. Viral cultures and P24 serum levels also remained unchanged. Lipid-based parenteral nutrition is safe and probably efficacious in AIDS. (Journal of Parenteral and Enteral Nutrition 16:165-167, 1992).
| Original language | English (US) |
|---|---|
| Pages (from-to) | 165-167 |
| Number of pages | 3 |
| Journal | Journal of Parenteral and Enteral Nutrition |
| Volume | 16 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1992 |
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ASJC Scopus subject areas
- Medicine (miscellaneous)
- Nutrition and Dietetics
- Food Science
Cite this
Clinical and Immunologic Effects of Lipid-Based Parenteral Nutrition in AIDS. / Singer, Pierre; Rubinstein, Arye; Askanazi, Jeffrey; Calvelli, Terry; Lazarus, Tadd; Kirvelä, Olli; Katz, David P.
In: Journal of Parenteral and Enteral Nutrition, Vol. 16, No. 2, 1992, p. 165-167.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Clinical and Immunologic Effects of Lipid-Based Parenteral Nutrition in AIDS
AU - Singer, Pierre
AU - Rubinstein, Arye
AU - Askanazi, Jeffrey
AU - Calvelli, Terry
AU - Lazarus, Tadd
AU - Kirvelä, Olli
AU - Katz, David P.
PY - 1992
Y1 - 1992
N2 - The effect of lipid-based parenteral nutrition was assessed in eight patients with AIDS and weight loss of 10% or greater. All patients received home parenteral nutrition consisting of a lipid-based system with 50% of nonprotein calories given as fat. Measurements were made of body weight, serum albumin, and immune function as assessed by mitogen responses, P24 antigen levels and T-cell counts. Over a period of 2 months, weight gain and improved well-being were noted in all patients. An improved in vitro lymphocyte mitogenic response to phytohemagglutinin and to concanavalin A was also noted. No change in T-cell subsets was observed. Viral cultures and P24 serum levels also remained unchanged. Lipid-based parenteral nutrition is safe and probably efficacious in AIDS. (Journal of Parenteral and Enteral Nutrition 16:165-167, 1992).
AB - The effect of lipid-based parenteral nutrition was assessed in eight patients with AIDS and weight loss of 10% or greater. All patients received home parenteral nutrition consisting of a lipid-based system with 50% of nonprotein calories given as fat. Measurements were made of body weight, serum albumin, and immune function as assessed by mitogen responses, P24 antigen levels and T-cell counts. Over a period of 2 months, weight gain and improved well-being were noted in all patients. An improved in vitro lymphocyte mitogenic response to phytohemagglutinin and to concanavalin A was also noted. No change in T-cell subsets was observed. Viral cultures and P24 serum levels also remained unchanged. Lipid-based parenteral nutrition is safe and probably efficacious in AIDS. (Journal of Parenteral and Enteral Nutrition 16:165-167, 1992).
UR - http://www.scopus.com/inward/record.url?scp=0026544940&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026544940&partnerID=8YFLogxK
U2 - 10.1177/0148607192016002165
DO - 10.1177/0148607192016002165
M3 - Article
C2 - 1556814
AN - SCOPUS:0026544940
VL - 16
SP - 165
EP - 167
JO - Journal of Parenteral and Enteral Nutrition
JF - Journal of Parenteral and Enteral Nutrition
SN - 0148-6071
IS - 2
ER -