Classification and definition of major flares in SLE clinical trials

Michelle Petri; Jill Buyon; Mimi Kim

doi:10.1191/096120399680411281

Classification and definition of major flares in SLE clinical trials

Michelle Petri, Jill Buyon, Mimi Kim

Research output: Contribution to journal › Review article › peer-review

240 Scopus citations

Abstract

Multiple reliable and valid disease activities indices exist and have been used successfully in longitudinal studies. However, the definition of flare, using these intruments, has not been universally decided or accepted. Because flare is one of the three major patterns of lupus activity, it will remain an important outcome measure in both longitudinal and clinical trial studies.

Original language	English (US)
Pages (from-to)	685-691
Number of pages	7
Journal	Lupus
Volume	8
Issue number	8
DOIs	https://doi.org/10.1191/096120399680411281
State	Published - 1999
Externally published	Yes

Keywords

Disease activity
Flare
SLEDAI
Systemic lupus erythematosus

ASJC Scopus subject areas

Rheumatology

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10.1191/096120399680411281

Cite this

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title = "Classification and definition of major flares in SLE clinical trials",

abstract = "Multiple reliable and valid disease activities indices exist and have been used successfully in longitudinal studies. However, the definition of flare, using these intruments, has not been universally decided or accepted. Because flare is one of the three major patterns of lupus activity, it will remain an important outcome measure in both longitudinal and clinical trial studies.",

keywords = "Disease activity, Flare, SLEDAI, Systemic lupus erythematosus",

author = "Michelle Petri and Jill Buyon and Mimi Kim",

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AU - Buyon, Jill

AU - Kim, Mimi

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AB - Multiple reliable and valid disease activities indices exist and have been used successfully in longitudinal studies. However, the definition of flare, using these intruments, has not been universally decided or accepted. Because flare is one of the three major patterns of lupus activity, it will remain an important outcome measure in both longitudinal and clinical trial studies.

KW - Disease activity

KW - Flare

KW - SLEDAI

KW - Systemic lupus erythematosus

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Classification and definition of major flares in SLE clinical trials

Abstract

Keywords

ASJC Scopus subject areas

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