Classification and definition of major flares in SLE clinical trials

Michelle Petri, Jill Buyon, Mimi Kim

Research output: Contribution to journalReview article

176 Scopus citations


Multiple reliable and valid disease activities indices exist and have been used successfully in longitudinal studies. However, the definition of flare, using these intruments, has not been universally decided or accepted. Because flare is one of the three major patterns of lupus activity, it will remain an important outcome measure in both longitudinal and clinical trial studies.

Original languageEnglish (US)
Pages (from-to)685-691
Number of pages7
Issue number8
StatePublished - Nov 18 1999
Externally publishedYes


  • Disease activity
  • Flare
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Rheumatology

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