Abstract
Sequential blood sampling every 30 min was performed in six adolescent males. Samples were analyzed for serum phosphate ((P<inf>i</inf>) total calcium (Ca<inf>T</inf>) and blood ionized calcium (Ca<sup>++</sup>) concentrations. A circadian (24-h) pattern was observed for each mineral 1) Ca<sup>++</sup> concentrations followed a U-shaped curve with a peak at 11 AM and a trough at 3:30 PM; 2) Ca<inf>T</inf> concentrations followed a W-shaped curve with maxima at 11 and 1 AM and troughs at 5 AM and 6 PM and 3) P<inf>i</inf> concentrations followed an M-shaped curve with peaks at 4 PM and 3:30 AM. The overall mineral patterns were similar in shape to those previously decribed in adult males. In contrast however the amplitude of the P<inf>i</inf> fluctuations were considerably greater in the adolescents compared with that in adults (3.0 mg/dl versus 1.2 mg/dl). The Ca<sup>++</sup> pattern diverged from the Ca<inf>T</inf> pattern during the nocturnal phase to an extent that neither pattern could be predicted from the other. Ultradian rhythms were found in some of the time series mineral data sets however no single frequency encompassed all subjects for each circulating mineral.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 456-462 |
| Number of pages | 7 |
| Journal | Pediatric Research |
| Volume | 18 |
| Issue number | 5 |
| State | Published - 1984 |
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ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
Cite this
Circadian rhythms of blood minerals during adolescence. / Markowitz, Morri E.; Rosen, John F.; Laxminarayan, Swamy; Mizruchi, Mark.
In: Pediatric Research, Vol. 18, No. 5, 1984, p. 456-462.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Circadian rhythms of blood minerals during adolescence
AU - Markowitz, Morri E.
AU - Rosen, John F.
AU - Laxminarayan, Swamy
AU - Mizruchi, Mark
PY - 1984
Y1 - 1984
N2 - Sequential blood sampling every 30 min was performed in six adolescent males. Samples were analyzed for serum phosphate ((Pi) total calcium (CaT) and blood ionized calcium (Ca++) concentrations. A circadian (24-h) pattern was observed for each mineral 1) Ca++ concentrations followed a U-shaped curve with a peak at 11 AM and a trough at 3:30 PM; 2) CaT concentrations followed a W-shaped curve with maxima at 11 and 1 AM and troughs at 5 AM and 6 PM and 3) Pi concentrations followed an M-shaped curve with peaks at 4 PM and 3:30 AM. The overall mineral patterns were similar in shape to those previously decribed in adult males. In contrast however the amplitude of the Pi fluctuations were considerably greater in the adolescents compared with that in adults (3.0 mg/dl versus 1.2 mg/dl). The Ca++ pattern diverged from the CaT pattern during the nocturnal phase to an extent that neither pattern could be predicted from the other. Ultradian rhythms were found in some of the time series mineral data sets however no single frequency encompassed all subjects for each circulating mineral.
AB - Sequential blood sampling every 30 min was performed in six adolescent males. Samples were analyzed for serum phosphate ((Pi) total calcium (CaT) and blood ionized calcium (Ca++) concentrations. A circadian (24-h) pattern was observed for each mineral 1) Ca++ concentrations followed a U-shaped curve with a peak at 11 AM and a trough at 3:30 PM; 2) CaT concentrations followed a W-shaped curve with maxima at 11 and 1 AM and troughs at 5 AM and 6 PM and 3) Pi concentrations followed an M-shaped curve with peaks at 4 PM and 3:30 AM. The overall mineral patterns were similar in shape to those previously decribed in adult males. In contrast however the amplitude of the Pi fluctuations were considerably greater in the adolescents compared with that in adults (3.0 mg/dl versus 1.2 mg/dl). The Ca++ pattern diverged from the CaT pattern during the nocturnal phase to an extent that neither pattern could be predicted from the other. Ultradian rhythms were found in some of the time series mineral data sets however no single frequency encompassed all subjects for each circulating mineral.
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M3 - Article
C2 - 6728572
AN - SCOPUS:0021324685
VL - 18
SP - 456
EP - 462
JO - Pediatric Research
JF - Pediatric Research
SN - 0031-3998
IS - 5
ER -