Ciliary beat frequency is controlled by a dynein light chain phosphorylation

P. Satir, K. Barkalow, T. Hamasaki

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

cAMP-dependent phosphorylation of a 29-kDa axonemal polypeptide (p29) increases the swimming speed of permeabilized Paramecium and in vitro translocation velocity of bovine brain microtubules over 22S dynein extracted from Paramecium axonemes. A quantitative relationship between microtubule translocation velocity and beat frequency is developed. We conclude thai p29 acts as a regulatory light chain of outer arm dynein in the control of ciliary best frequency.

Original languageEnglish (US)
Pages (from-to)222s
JournalBiophysical Journal
Volume68
Issue number4 SUPPL.
StatePublished - Jan 1 1995

ASJC Scopus subject areas

  • Biophysics

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    Satir, P., Barkalow, K., & Hamasaki, T. (1995). Ciliary beat frequency is controlled by a dynein light chain phosphorylation. Biophysical Journal, 68(4 SUPPL.), 222s.