cAMP-dependent phosphorylation of a 29-kDa axonemal polypeptide (p29) increases the swimming speed of permeabilized Paramecium and in vitro translocation velocity of bovine brain microtubules over 22S dynein extracted from Paramecium axonemes. A quantitative relationship between microtubule translocation velocity and beat frequency is developed. We conclude thai p29 acts as a regulatory light chain of outer arm dynein in the control of ciliary best frequency.
|Original language||English (US)|
|Issue number||4 SUPPL.|
|State||Published - Jan 1 1995|
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