Cigarette smoking and breast cancer

T. E. Rohan, J. A. Baron

Research output: Contribution to journalArticlepeer-review

53 Scopus citations

Abstract

Rohan, T. E., and J. A. Baron (Dartmouth Medical School, Hanover, NH 03756). Cigarette smoking and breast cancer. Am J Epidemiol 1989; 129:36-42.The relation between cigarette smoking and the risk of breast cancer in women was investigated in a population-based case-control study conducted in Adelaide, Australia during 1982-1984. Cases were identified through the South Australian Central Cancer Registry, and, for each case, one age-matched control was selected from the electoral register; in all, 451 case-control pairs were enrolled. Overall, no clear association was found between ever or current smoking and breast cancer risk. In a subgroup analysis, premenopausal ex-smokers were observed to have an increased risk (estimated odds ratio=2.3). The absence of a protective effect of cigarette smoking on breast cancer risk may reflect the relatively weak estrogen dependence of breast cancer, or the nature of its hormone dependence.

Original languageEnglish (US)
Pages (from-to)36-42
Number of pages7
JournalAmerican Journal of Epidemiology
Volume129
Issue number1
DOIs
StatePublished - Jan 1989
Externally publishedYes

Keywords

  • Breast neoplasms
  • Smoking

ASJC Scopus subject areas

  • Epidemiology

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