Graft-versus-host disease (GVHD) is a common complication of allogeneic bone marrow transplantation (allo- BMT). Ocular surface disease (OSD) is one of the most commom manifestation of chronic ocular GVHD, yet little is known about it. In this article, we review the available literature on this condition and present results from our study of the manifestations of OSD in the chronic phse (>3 months duration) post allo-BMT. Our study consisted of a retrospective chart review of 62 allo-BMT patients with chronic OSD evaluated at our center between 1995 and 2002. The clinical features, systemic associations, treatmeant, and status of OSD at the last follow-up presented and discussed in the context of other reports of OSD in GVHD.
- Allogeneic bone marrow transplantation
- Graft-versus-host disease
- Ocular surface disease
ASJC Scopus subject areas