Chronic kidney disease

A life course health development perspective

Patrick D. Brophy, Jennifer R. Charlton, J. Bryan Carmody, Kimberly J. Reidy, Lyndsay Harshman, Jeffrey Segar, David Askenazi, David Shoham, Susan P. Bagby

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

Chronic kidney disease (CKD) reflects life events that range from maternal-fetal influences to geriatric exposures. The global direct and indirect costs of CKD are high and include maternal-neonatal hospitalization and treatment, acute kidney injury, dialysis and transplant, missed work, and medications, to name a few. The impact of poor diet, adverse childhood experiences, medication use, and failure to follow consistent public health standards are increasingly appreciated as key influences in the development of CKD. Socioeconomic factors can significantly influence the timing and phenotypic expression in people at risk for developing CKD, although more research is needed to understand these mechanisms. In general, biomedicine has been focused on treating well-established CKD morbidity. This strategy has been short sighted and costly. A more cost-effective approach would focus on early life interventions that hold the potential for mitigating CKD risk and its sequelae. This chapter applies the life course health development principles to review determinants and pathways for CKD evolution and identifies of the gaps in our knowledgebase. We also discuss several research strategies for evaluating the life course health development of CKD.

Original languageEnglish (US)
Title of host publicationHandbook of Life Course Health Development
PublisherSpringer International Publishing
Pages375-401
Number of pages27
ISBN (Electronic)9783319471433
ISBN (Print)9783319471419
DOIs
StatePublished - Jan 1 2017

Fingerprint

Chronic Renal Insufficiency
Disease
Health
health
medication
Mothers
Costs and Cost Analysis
biomedicine
Knowledge Bases
Life course
Kidney
socioeconomic factors
geriatrics
costs
hospitalization
Research
Acute Kidney Injury
Geriatrics
morbidity
chronic illness

ASJC Scopus subject areas

  • Psychology(all)
  • Social Sciences(all)
  • Economics, Econometrics and Finance(all)
  • Business, Management and Accounting(all)
  • Medicine(all)

Cite this

Brophy, P. D., Charlton, J. R., Carmody, J. B., Reidy, K. J., Harshman, L., Segar, J., ... Bagby, S. P. (2017). Chronic kidney disease: A life course health development perspective. In Handbook of Life Course Health Development (pp. 375-401). Springer International Publishing. https://doi.org/10.1007/978-3-319-47143-3_16

Chronic kidney disease : A life course health development perspective. / Brophy, Patrick D.; Charlton, Jennifer R.; Carmody, J. Bryan; Reidy, Kimberly J.; Harshman, Lyndsay; Segar, Jeffrey; Askenazi, David; Shoham, David; Bagby, Susan P.

Handbook of Life Course Health Development. Springer International Publishing, 2017. p. 375-401.

Research output: Chapter in Book/Report/Conference proceedingChapter

Brophy, PD, Charlton, JR, Carmody, JB, Reidy, KJ, Harshman, L, Segar, J, Askenazi, D, Shoham, D & Bagby, SP 2017, Chronic kidney disease: A life course health development perspective. in Handbook of Life Course Health Development. Springer International Publishing, pp. 375-401. https://doi.org/10.1007/978-3-319-47143-3_16
Brophy PD, Charlton JR, Carmody JB, Reidy KJ, Harshman L, Segar J et al. Chronic kidney disease: A life course health development perspective. In Handbook of Life Course Health Development. Springer International Publishing. 2017. p. 375-401 https://doi.org/10.1007/978-3-319-47143-3_16
Brophy, Patrick D. ; Charlton, Jennifer R. ; Carmody, J. Bryan ; Reidy, Kimberly J. ; Harshman, Lyndsay ; Segar, Jeffrey ; Askenazi, David ; Shoham, David ; Bagby, Susan P. / Chronic kidney disease : A life course health development perspective. Handbook of Life Course Health Development. Springer International Publishing, 2017. pp. 375-401
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