We have localized a cDNA fragment that codes for human DNA polymerase-β. Using somatic cell and in situ hybridization techniques, this cDNA was cloned by screening a human KM-3 cell cDNA librairy in λgt 11 for expression of fused β-galactosidase-human DNA polymerase-β proteins. We have mapped this human polymerase-β gene to the short arm of chromosome 8 in the subregion 8p11→p12.
|Original language||English (US)|
|Number of pages||4|
|Journal||Cytogenetics and Cell Genetics|
|Publication status||Published - Jan 1 1988|
ASJC Scopus subject areas
- Cell Biology