Chromosome sublocalization of a cDNA for human DNA polymerase-β to 8p11→p12

L. A. Cannizzaro, F. J. Bollum, K. Huebner, C. M. Croce, L. C. Cheung, X. Xu, B. K. Hecht, F. Hecht, L. M.S. Chang

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Abstract

We have localized a cDNA fragment that codes for human DNA polymerase-β. Using somatic cell and in situ hybridization techniques, this cDNA was cloned by screening a human KM-3 cell cDNA librairy in λgt 11 for expression of fused β-galactosidase-human DNA polymerase-β proteins. We have mapped this human polymerase-β gene to the short arm of chromosome 8 in the subregion 8p11→p12.

Original languageEnglish (US)
Pages (from-to)121-124
Number of pages4
JournalCytogenetics and Cell Genetics
Volume47
Issue number3
Publication statusPublished - Jan 1 1988

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ASJC Scopus subject areas

  • Genetics
  • Cell Biology

Cite this

Cannizzaro, L. A., Bollum, F. J., Huebner, K., Croce, C. M., Cheung, L. C., Xu, X., ... Chang, L. M. S. (1988). Chromosome sublocalization of a cDNA for human DNA polymerase-β to 8p11→p12. Cytogenetics and Cell Genetics, 47(3), 121-124.