Chromosome abnormalities in meningiomas

Junsuke Katsuyama, Peter R. Papenhausen, Fritz Herz, Pasko Gazivoda, Asao Hirano, Leopold G. Koss

Research output: Contribution to journalArticle

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Abstract

Cytogenetic analyses of eight meningiomas grown in culture for 1 week are reported. Normal karyotypes were found in three cases and hypodiploidy in the remaining five. In the five hypodiploid meningiomas, one chromosome #22 was missing in four cases, and one case exhibited a 22q- deletion. In four of these five cases, chromosome #14 was either lost or altered. Chromosome #1 was lost or altered in three, and chromosome #6 in two. These findings lend further support for the association of total or partial loss of chromosome #22 in meningiomas and suggest the involvement of other chromosomes in the clonal evolution of these tumors.

Original languageEnglish (US)
Pages (from-to)63-68
Number of pages6
JournalCancer Genetics and Cytogenetics
Volume22
Issue number1
DOIs
StatePublished - 1986

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Meningioma
Chromosome Aberrations
Chromosomes, Human, Pair 22
Clonal Evolution
Chromosomes, Human, Pair 14
Chromosomes, Human, Pair 6
Chromosomes, Human, Pair 1
Cytogenetic Analysis
Karyotype
Chromosomes
Neoplasms

ASJC Scopus subject areas

  • Cancer Research
  • Genetics
  • Molecular Biology

Cite this

Katsuyama, J., Papenhausen, P. R., Herz, F., Gazivoda, P., Hirano, A., & Koss, L. G. (1986). Chromosome abnormalities in meningiomas. Cancer Genetics and Cytogenetics, 22(1), 63-68. https://doi.org/10.1016/0165-4608(86)90138-X

Chromosome abnormalities in meningiomas. / Katsuyama, Junsuke; Papenhausen, Peter R.; Herz, Fritz; Gazivoda, Pasko; Hirano, Asao; Koss, Leopold G.

In: Cancer Genetics and Cytogenetics, Vol. 22, No. 1, 1986, p. 63-68.

Research output: Contribution to journalArticle

Katsuyama, J, Papenhausen, PR, Herz, F, Gazivoda, P, Hirano, A & Koss, LG 1986, 'Chromosome abnormalities in meningiomas', Cancer Genetics and Cytogenetics, vol. 22, no. 1, pp. 63-68. https://doi.org/10.1016/0165-4608(86)90138-X
Katsuyama J, Papenhausen PR, Herz F, Gazivoda P, Hirano A, Koss LG. Chromosome abnormalities in meningiomas. Cancer Genetics and Cytogenetics. 1986;22(1):63-68. https://doi.org/10.1016/0165-4608(86)90138-X
Katsuyama, Junsuke ; Papenhausen, Peter R. ; Herz, Fritz ; Gazivoda, Pasko ; Hirano, Asao ; Koss, Leopold G. / Chromosome abnormalities in meningiomas. In: Cancer Genetics and Cytogenetics. 1986 ; Vol. 22, No. 1. pp. 63-68.
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