Chromosome abnormalities in meningiomas

Junsuke Katsuyama; Peter R. Papenhausen; Fritz Herz; Pasko Gazivoda; Asao Hirano; Leopold G. Koss

doi:10.1016/0165-4608(86)90138-X

Chromosome abnormalities in meningiomas

Junsuke Katsuyama, Peter R. Papenhausen, Fritz Herz, Pasko Gazivoda, Asao Hirano, Leopold G. Koss

Pathology

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54 Scopus citations

Abstract

Cytogenetic analyses of eight meningiomas grown in culture for 1 week are reported. Normal karyotypes were found in three cases and hypodiploidy in the remaining five. In the five hypodiploid meningiomas, one chromosome #22 was missing in four cases, and one case exhibited a 22q- deletion. In four of these five cases, chromosome #14 was either lost or altered. Chromosome #1 was lost or altered in three, and chromosome #6 in two. These findings lend further support for the association of total or partial loss of chromosome #22 in meningiomas and suggest the involvement of other chromosomes in the clonal evolution of these tumors.

Original language	English (US)
Pages (from-to)	63-68
Number of pages	6
Journal	Cancer Genetics and Cytogenetics
Volume	22
Issue number	1
DOIs	https://doi.org/10.1016/0165-4608(86)90138-X
Publication status	Published - May 1986

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ASJC Scopus subject areas

Molecular Biology
Genetics
Cancer Research

Cite this

Katsuyama, J., Papenhausen, P. R., Herz, F., Gazivoda, P., Hirano, A., & Koss, L. G. (1986). Chromosome abnormalities in meningiomas. Cancer Genetics and Cytogenetics, 22(1), 63-68. https://doi.org/10.1016/0165-4608(86)90138-X

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10.1016/0165-4608(86)90138-X