Abstract
Cytogenetic analyses of eight meningiomas grown in culture for 1 week are reported. Normal karyotypes were found in three cases and hypodiploidy in the remaining five. In the five hypodiploid meningiomas, one chromosome #22 was missing in four cases, and one case exhibited a 22q- deletion. In four of these five cases, chromosome #14 was either lost or altered. Chromosome #1 was lost or altered in three, and chromosome #6 in two. These findings lend further support for the association of total or partial loss of chromosome #22 in meningiomas and suggest the involvement of other chromosomes in the clonal evolution of these tumors.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 63-68 |
| Number of pages | 6 |
| Journal | Cancer Genetics and Cytogenetics |
| Volume | 22 |
| Issue number | 1 |
| DOIs | |
| State | Published - May 1986 |
ASJC Scopus subject areas
- Molecular Biology
- Genetics
- Cancer Research
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Cite this
Katsuyama, J., Papenhausen, P. R., Herz, F., Gazivoda, P., Hirano, A., & Koss, L. G. (1986). Chromosome abnormalities in meningiomas. Cancer Genetics and Cytogenetics, 22(1), 63-68. https://doi.org/10.1016/0165-4608(86)90138-X