Chromosome abnormalities in meningiomas

Junsuke Katsuyama, Peter R. Papenhausen, Fritz Herz, Pasko Gazivoda, Asao Hirano, Leopold G. Koss

Research output: Contribution to journalArticlepeer-review

54 Scopus citations


Cytogenetic analyses of eight meningiomas grown in culture for 1 week are reported. Normal karyotypes were found in three cases and hypodiploidy in the remaining five. In the five hypodiploid meningiomas, one chromosome #22 was missing in four cases, and one case exhibited a 22q- deletion. In four of these five cases, chromosome #14 was either lost or altered. Chromosome #1 was lost or altered in three, and chromosome #6 in two. These findings lend further support for the association of total or partial loss of chromosome #22 in meningiomas and suggest the involvement of other chromosomes in the clonal evolution of these tumors.

Original languageEnglish (US)
Pages (from-to)63-68
Number of pages6
JournalCancer Genetics and Cytogenetics
Issue number1
StatePublished - May 1986

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research


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