TY - JOUR
T1 - Chromosome abnormalities in meningiomas
AU - Katsuyama, Junsuke
AU - Papenhausen, Peter R.
AU - Herz, Fritz
AU - Gazivoda, Pasko
AU - Hirano, Asao
AU - Koss, Leopold G.
PY - 1986/5
Y1 - 1986/5
N2 - Cytogenetic analyses of eight meningiomas grown in culture for 1 week are reported. Normal karyotypes were found in three cases and hypodiploidy in the remaining five. In the five hypodiploid meningiomas, one chromosome #22 was missing in four cases, and one case exhibited a 22q- deletion. In four of these five cases, chromosome #14 was either lost or altered. Chromosome #1 was lost or altered in three, and chromosome #6 in two. These findings lend further support for the association of total or partial loss of chromosome #22 in meningiomas and suggest the involvement of other chromosomes in the clonal evolution of these tumors.
AB - Cytogenetic analyses of eight meningiomas grown in culture for 1 week are reported. Normal karyotypes were found in three cases and hypodiploidy in the remaining five. In the five hypodiploid meningiomas, one chromosome #22 was missing in four cases, and one case exhibited a 22q- deletion. In four of these five cases, chromosome #14 was either lost or altered. Chromosome #1 was lost or altered in three, and chromosome #6 in two. These findings lend further support for the association of total or partial loss of chromosome #22 in meningiomas and suggest the involvement of other chromosomes in the clonal evolution of these tumors.
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U2 - 10.1016/0165-4608(86)90138-X
DO - 10.1016/0165-4608(86)90138-X
M3 - Article
C2 - 3456829
AN - SCOPUS:0022521431
VL - 22
SP - 63
EP - 68
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
SN - 0165-4608
IS - 1
ER -
