Choroidal thickness profiles in myopic eyes of young adults in the correction of myopia evaluation trial cohort

Elise Harb; Leslie Hyman; Jane Gwiazda; Wendy Marsh-Tootle; Qinghua Zhang; Wei Hou; Thomas T. Norton; Katherine Weise; Keri Dirkes; Linda M. Zangwill; Li Deng; Kenneth Grice; Christine Fortunato; Cara Weber; Alexandra Beale; David Kern; Sally Bittinger; Debanjali Ghosh; Rosemarie Smith; Rosanna Pacella; M. Cristina Leske; Mohamed Hussein; Li Ming Dong; Melissa Fazzari; Lynette Dias; Rachel Harrison; Wen Zhu; Elinor Schoenfeld; Ying Wang; Ahmed Yassin; Elissa Schnall; Cristi Rau; Jennifer Thomas; Marcela Wasserman; Yi Ju Chen; Sakeena Ahmed; Leanne Merill; Lauretta Passanant; Maria Rodriguez; Allison Schmertz; Ann Park; Phyllis Neuschwender; Geeta Veeraraghavan; Angela Santomarco; Laura Sisti; Lydia Seib; Donald Everett; Marcela Frazier; Catherine Baldwin; Carey Dillard; Kristine Becker; James Raley; Angela Rawden; Nicholas Harris; Trana Mars; Robert Rutstein; Daniel Kurtz; Erik Weissberg; Bruce Moore; Robert Owens; Sheila Martin; Joanne Bolden; Justin Smith; Benny Jaramillo; Stacy Hamlett; Laura Vasilakos; Sarah Gladstone; Chris Owens; Patricia Kowalski; Jennifer Hazelwood; Ruth Manny; Connie Crossnoe; Karen Fern; Heather Anderson; Sheila Deatherage; Charles Dudonis; Sally Henry; Jennifer McLeod; Mamie Batres; Julio Quiralte; Giselle Garza; Gabynely Solis; Joan Do; Andy Ketcham; Mitchell Scheiman; Kathleen Zinzer; Karen Pollack; Timothy Lancaster; Theresa Elliott; Mark Bernhardt; Daniel Ferrara; Jeff Miles; Scott Wilkins; Renee Wilkins; Jennifer Nicole Lynch; Dawn D'Antonio; Lindsey Lear; Sandy Dang; Charles Sporer; Mary Jameson; Abby Grossman; Mariel Torres; Heather Jones; Melissa Madigan-Carr; Theresa Sanogo; Joann Bailey; Robert Hardy; Argye Hillis; Donald Mutti; Richard Stone; Carol Taylor

doi:10.1016/j.ajo.2015.04.018

Choroidal thickness profiles in myopic eyes of young adults in the correction of myopia evaluation trial cohort

Elise Harb, Leslie Hyman, Jane Gwiazda, Wendy Marsh-Tootle, Qinghua Zhang, Wei Hou, Thomas T. Norton, Katherine Weise, Keri Dirkes, Linda M. Zangwill, Li Deng, Kenneth Grice, Christine Fortunato, Cara Weber, Alexandra Beale, David Kern, Sally Bittinger, Debanjali Ghosh, Rosemarie Smith, Rosanna PacellaM. Cristina Leske, Mohamed Hussein, Li Ming Dong, Melissa Fazzari, Lynette Dias, Rachel Harrison, Wen Zhu, Elinor Schoenfeld, Ying Wang, Ahmed Yassin, Elissa Schnall, Cristi Rau, Jennifer Thomas, Marcela Wasserman, Yi Ju Chen, Sakeena Ahmed, Leanne Merill, Lauretta Passanant, Maria Rodriguez, Allison Schmertz, Ann Park, Phyllis Neuschwender, Geeta Veeraraghavan, Angela Santomarco, Laura Sisti, Lydia Seib, Donald Everett, Marcela Frazier, Catherine Baldwin, Carey Dillard, Kristine Becker, James Raley, Angela Rawden, Nicholas Harris, Trana Mars, Robert Rutstein, Daniel Kurtz, Erik Weissberg, Bruce Moore, Robert Owens, Sheila Martin, Joanne Bolden, Justin Smith, Benny Jaramillo, Stacy Hamlett, Laura Vasilakos, Sarah Gladstone, Chris Owens, Patricia Kowalski, Jennifer Hazelwood, Ruth Manny, Connie Crossnoe, Karen Fern, Heather Anderson, Sheila Deatherage, Charles Dudonis, Sally Henry, Jennifer McLeod, Mamie Batres, Julio Quiralte, Giselle Garza, Gabynely Solis, Joan Do, Andy Ketcham, Mitchell Scheiman, Kathleen Zinzer, Karen Pollack, Timothy Lancaster, Theresa Elliott, Mark Bernhardt, Daniel Ferrara, Jeff Miles, Scott Wilkins, Renee Wilkins, Jennifer Nicole Lynch, Dawn D'Antonio, Lindsey Lear, Sandy Dang, Charles Sporer, Mary Jameson, Abby Grossman, Mariel Torres, Heather Jones, Melissa Madigan-Carr, Theresa Sanogo, Joann Bailey, Robert Hardy, Argye Hillis, Donald Mutti, Richard Stone, Carol Taylor

Research output: Contribution to journal › Article › peer-review

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Abstract

Purpose To examine the relationship of choroidal thickness with axial length (AL) and myopia in young adult eyes in the ethnically diverse Correction of Myopia Evaluation Trial (COMET) cohort. Design Cross-sectional, multicenter study. Methods In addition to measures of myopia by cycloplegic autorefraction and AL by A-scan ultrasonography, participants underwent optical coherence tomography imaging of the choroid in both eyes at their last visit (14 years after baseline). Using digital calipers, 2 independent readers measured choroidal thickness in the right eye (left eye if poor quality; n = 37) at 7 locations: fovea and 750, 1500, and 2250 μm nasal (N) and temporal (T) to the fovea. Results Choroidal thickness measurements were available from 294 of 346 (85%) imaged participants (mean age: 24.3 ± 1.4 years; 44.9% male) with mean myopia of -5.3 ± 2.0 diopters and mean AL of 25.5 ± 1.0 mm. Overall, choroidal thickness varied by location (P <.0001) and was thickest at the fovea (273.8 ± 70.9 μm) and thinnest nasally (N2250, 191.5 ± 69.3 μm). Multivariable analyses showed significantly thinner choroids in eyes with more myopia and longer AL at all locations except T2250 (P ≤.001) and presence of peripapillary crescent at all locations except T1500 and T2250 (P ≤.0001). Choroidal thickness varied by ethnicity at N2250 (P <.0001), with Asians having the thinnest and African Americans the thickest choroids. Conclusion Choroids are thinner in longer, more myopic young adult eyes. The thinning was most prominent nasally and in eyes with a crescent. In the furthest nasal location, ethnicity was associated with choroidal thickness. The findings suggest that choroidal thickness should be evaluated, especially in the nasal regions where myopic degenerations are most commonly seen clinically.

Original language	English (US)
Pages (from-to)	62-71.e2
Journal	American journal of ophthalmology
Volume	160
Issue number	1
DOIs	https://doi.org/10.1016/j.ajo.2015.04.018
State	Published - Jul 1 2015
Externally published	Yes

ASJC Scopus subject areas

Ophthalmology

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10.1016/j.ajo.2015.04.018

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Harb, E., Hyman, L., Gwiazda, J., Marsh-Tootle, W., Zhang, Q., Hou, W., Norton, T. T., Weise, K., Dirkes, K., Zangwill, L. M., Deng, L., Grice, K., Fortunato, C., Weber, C., Beale, A., Kern, D., Bittinger, S., Ghosh, D., Smith, R., ... Taylor, C. (2015). Choroidal thickness profiles in myopic eyes of young adults in the correction of myopia evaluation trial cohort. American journal of ophthalmology, 160(1), 62-71.e2. https://doi.org/10.1016/j.ajo.2015.04.018

Harb, E, Hyman, L, Gwiazda, J, Marsh-Tootle, W, Zhang, Q, Hou, W, Norton, TT, Weise, K, Dirkes, K, Zangwill, LM, Deng, L, Grice, K, Fortunato, C, Weber, C, Beale, A, Kern, D, Bittinger, S, Ghosh, D, Smith, R, Pacella, R, Leske, MC, Hussein, M, Dong, LM, Fazzari, M, Dias, L, Harrison, R, Zhu, W, Schoenfeld, E, Wang, Y, Yassin, A, Schnall, E, Rau, C, Thomas, J, Wasserman, M, Chen, YJ, Ahmed, S, Merill, L, Passanant, L, Rodriguez, M, Schmertz, A, Park, A, Neuschwender, P, Veeraraghavan, G, Santomarco, A, Sisti, L, Seib, L, Everett, D, Frazier, M, Baldwin, C, Dillard, C, Becker, K, Raley, J, Rawden, A, Harris, N, Mars, T, Rutstein, R, Kurtz, D, Weissberg, E, Moore, B, Owens, R, Martin, S, Bolden, J, Smith, J, Jaramillo, B, Hamlett, S, Vasilakos, L, Gladstone, S, Owens, C, Kowalski, P, Hazelwood, J, Manny, R, Crossnoe, C, Fern, K, Anderson, H, Deatherage, S, Dudonis, C, Henry, S, McLeod, J, Batres, M, Quiralte, J, Garza, G, Solis, G, Do, J, Ketcham, A, Scheiman, M, Zinzer, K, Pollack, K, Lancaster, T, Elliott, T, Bernhardt, M, Ferrara, D, Miles, J, Wilkins, S, Wilkins, R, Nicole Lynch, J, D'Antonio, D, Lear, L, Dang, S, Sporer, C, Jameson, M, Grossman, A, Torres, M, Jones, H, Madigan-Carr, M, Sanogo, T, Bailey, J, Hardy, R, Hillis, A, Mutti, D, Stone, R & Taylor, C 2015, 'Choroidal thickness profiles in myopic eyes of young adults in the correction of myopia evaluation trial cohort', American journal of ophthalmology, vol. 160, no. 1, pp. 62-71.e2. https://doi.org/10.1016/j.ajo.2015.04.018

@article{9c48e24a773846db8617878556b2d81a,

title = "Choroidal thickness profiles in myopic eyes of young adults in the correction of myopia evaluation trial cohort",

abstract = "Purpose To examine the relationship of choroidal thickness with axial length (AL) and myopia in young adult eyes in the ethnically diverse Correction of Myopia Evaluation Trial (COMET) cohort. Design Cross-sectional, multicenter study. Methods In addition to measures of myopia by cycloplegic autorefraction and AL by A-scan ultrasonography, participants underwent optical coherence tomography imaging of the choroid in both eyes at their last visit (14 years after baseline). Using digital calipers, 2 independent readers measured choroidal thickness in the right eye (left eye if poor quality; n = 37) at 7 locations: fovea and 750, 1500, and 2250 μm nasal (N) and temporal (T) to the fovea. Results Choroidal thickness measurements were available from 294 of 346 (85%) imaged participants (mean age: 24.3 ± 1.4 years; 44.9% male) with mean myopia of -5.3 ± 2.0 diopters and mean AL of 25.5 ± 1.0 mm. Overall, choroidal thickness varied by location (P <.0001) and was thickest at the fovea (273.8 ± 70.9 μm) and thinnest nasally (N2250, 191.5 ± 69.3 μm). Multivariable analyses showed significantly thinner choroids in eyes with more myopia and longer AL at all locations except T2250 (P ≤.001) and presence of peripapillary crescent at all locations except T1500 and T2250 (P ≤.0001). Choroidal thickness varied by ethnicity at N2250 (P <.0001), with Asians having the thinnest and African Americans the thickest choroids. Conclusion Choroids are thinner in longer, more myopic young adult eyes. The thinning was most prominent nasally and in eyes with a crescent. In the furthest nasal location, ethnicity was associated with choroidal thickness. The findings suggest that choroidal thickness should be evaluated, especially in the nasal regions where myopic degenerations are most commonly seen clinically.",

author = "Elise Harb and Leslie Hyman and Jane Gwiazda and Wendy Marsh-Tootle and Qinghua Zhang and Wei Hou and Norton, {Thomas T.} and Katherine Weise and Keri Dirkes and Zangwill, {Linda M.} and Li Deng and Kenneth Grice and Christine Fortunato and Cara Weber and Alexandra Beale and David Kern and Sally Bittinger and Debanjali Ghosh and Rosemarie Smith and Rosanna Pacella and Leske, {M. Cristina} and Mohamed Hussein and Dong, {Li Ming} and Melissa Fazzari and Lynette Dias and Rachel Harrison and Wen Zhu and Elinor Schoenfeld and Ying Wang and Ahmed Yassin and Elissa Schnall and Cristi Rau and Jennifer Thomas and Marcela Wasserman and Chen, {Yi Ju} and Sakeena Ahmed and Leanne Merill and Lauretta Passanant and Maria Rodriguez and Allison Schmertz and Ann Park and Phyllis Neuschwender and Geeta Veeraraghavan and Angela Santomarco and Laura Sisti and Lydia Seib and Donald Everett and Marcela Frazier and Catherine Baldwin and Carey Dillard and Kristine Becker and James Raley and Angela Rawden and Nicholas Harris and Trana Mars and Robert Rutstein and Daniel Kurtz and Erik Weissberg and Bruce Moore and Robert Owens and Sheila Martin and Joanne Bolden and Justin Smith and Benny Jaramillo and Stacy Hamlett and Laura Vasilakos and Sarah Gladstone and Chris Owens and Patricia Kowalski and Jennifer Hazelwood and Ruth Manny and Connie Crossnoe and Karen Fern and Heather Anderson and Sheila Deatherage and Charles Dudonis and Sally Henry and Jennifer McLeod and Mamie Batres and Julio Quiralte and Giselle Garza and Gabynely Solis and Joan Do and Andy Ketcham and Mitchell Scheiman and Kathleen Zinzer and Karen Pollack and Timothy Lancaster and Theresa Elliott and Mark Bernhardt and Daniel Ferrara and Jeff Miles and Scott Wilkins and Renee Wilkins and {Nicole Lynch}, Jennifer and Dawn D'Antonio and Lindsey Lear and Sandy Dang and Charles Sporer and Mary Jameson and Abby Grossman and Mariel Torres and Heather Jones and Melissa Madigan-Carr and Theresa Sanogo and Joann Bailey and Robert Hardy and Argye Hillis and Donald Mutti and Richard Stone and Carol Taylor",

note = "Funding Information: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Financial Disclosures: E.H.: received grant support from National Eye Institute (NEI, EY11752, EY023263). L.H.: received grant support from NEI (EY11805), member of Data and Safety Monitoring Board for unrelated NEI funded project, also receives grant support from National Institute of Dental and Craniofacial Research (NIDCR, USA, DE018886) for unrelated project. J.G.: received grant support from NEI (EY11756, EY023263). W.M.-T.: received grant support from NEI (EY11754). Q.Z.: received grant support from NEI (EY11805, EY023263). W.H.: received grant support from NEI (EY11805) and also from NIDCR, USA (DE018886) for unrelated project. T.T.N.: received grant support from NEI (EY11756, EY11754). K.W.: received grant support from NEI (EY11754). K.D.: received grant support from NEI (EY022589) and from Quark Pharmaceuticals (USA) for an unrelated project. L.Z.: received grant support from NEI (EY022589), received equipment and materials from Optovue, Inc, Heidelberg Engineering, Zeiss Meditec, and Topcon. Funding/Support: This study was supported by the following National Eye Institute (United States) grants: EY11805 , EY023263, EY11740 , EY11756 , EY11754 , EY11752 , EY11755 , and P30EY022589 . The sponsor or funding organization had no role in the reporting or interpretation of study data. All authors attest that they meet the current ICMJE requirements to qualify as authors. Publisher Copyright: {\textcopyright} 2015 BY ELSEVIER INC. ALL RIGHTS RESERVED.",

year = "2015",

month = jul,

day = "1",

doi = "10.1016/j.ajo.2015.04.018",

language = "English (US)",

volume = "160",

pages = "62--71.e2",

journal = "American Journal of Ophthalmology",

issn = "0002-9394",

publisher = "Elsevier USA",

number = "1",

}

TY - JOUR

T1 - Choroidal thickness profiles in myopic eyes of young adults in the correction of myopia evaluation trial cohort

AU - Harb, Elise

AU - Hyman, Leslie

AU - Gwiazda, Jane

AU - Marsh-Tootle, Wendy

AU - Zhang, Qinghua

AU - Hou, Wei

AU - Norton, Thomas T.

AU - Weise, Katherine

AU - Dirkes, Keri

AU - Zangwill, Linda M.

AU - Deng, Li

AU - Grice, Kenneth

AU - Fortunato, Christine

AU - Weber, Cara

AU - Beale, Alexandra

AU - Kern, David

AU - Bittinger, Sally

AU - Ghosh, Debanjali

AU - Smith, Rosemarie

AU - Pacella, Rosanna

AU - Leske, M. Cristina

AU - Hussein, Mohamed

AU - Dong, Li Ming

AU - Fazzari, Melissa

AU - Dias, Lynette

AU - Harrison, Rachel

AU - Zhu, Wen

AU - Schoenfeld, Elinor

AU - Wang, Ying

AU - Yassin, Ahmed

AU - Schnall, Elissa

AU - Rau, Cristi

AU - Thomas, Jennifer

AU - Wasserman, Marcela

AU - Chen, Yi Ju

AU - Ahmed, Sakeena

AU - Merill, Leanne

AU - Passanant, Lauretta

AU - Rodriguez, Maria

AU - Schmertz, Allison

AU - Park, Ann

AU - Neuschwender, Phyllis

AU - Veeraraghavan, Geeta

AU - Santomarco, Angela

AU - Sisti, Laura

AU - Seib, Lydia

AU - Everett, Donald

AU - Frazier, Marcela

AU - Baldwin, Catherine

AU - Dillard, Carey

AU - Becker, Kristine

AU - Raley, James

AU - Rawden, Angela

AU - Harris, Nicholas

AU - Mars, Trana

AU - Rutstein, Robert

AU - Kurtz, Daniel

AU - Weissberg, Erik

AU - Moore, Bruce

AU - Owens, Robert

AU - Martin, Sheila

AU - Bolden, Joanne

AU - Smith, Justin

AU - Jaramillo, Benny

AU - Hamlett, Stacy

AU - Vasilakos, Laura

AU - Gladstone, Sarah

AU - Owens, Chris

AU - Kowalski, Patricia

AU - Hazelwood, Jennifer

AU - Manny, Ruth

AU - Crossnoe, Connie

AU - Fern, Karen

AU - Anderson, Heather

AU - Deatherage, Sheila

AU - Dudonis, Charles

AU - Henry, Sally

AU - McLeod, Jennifer

AU - Batres, Mamie

AU - Quiralte, Julio

AU - Garza, Giselle

AU - Solis, Gabynely

AU - Do, Joan

AU - Ketcham, Andy

AU - Scheiman, Mitchell

AU - Zinzer, Kathleen

AU - Pollack, Karen

AU - Lancaster, Timothy

AU - Elliott, Theresa

AU - Bernhardt, Mark

AU - Ferrara, Daniel

AU - Miles, Jeff

AU - Wilkins, Scott

AU - Wilkins, Renee

AU - Nicole Lynch, Jennifer

AU - D'Antonio, Dawn

AU - Lear, Lindsey

AU - Dang, Sandy

AU - Sporer, Charles

AU - Jameson, Mary

AU - Grossman, Abby

AU - Torres, Mariel

AU - Jones, Heather

AU - Madigan-Carr, Melissa

AU - Sanogo, Theresa

AU - Bailey, Joann

AU - Hardy, Robert

AU - Hillis, Argye

AU - Mutti, Donald

AU - Stone, Richard

AU - Taylor, Carol

N1 - Funding Information: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Financial Disclosures: E.H.: received grant support from National Eye Institute (NEI, EY11752, EY023263). L.H.: received grant support from NEI (EY11805), member of Data and Safety Monitoring Board for unrelated NEI funded project, also receives grant support from National Institute of Dental and Craniofacial Research (NIDCR, USA, DE018886) for unrelated project. J.G.: received grant support from NEI (EY11756, EY023263). W.M.-T.: received grant support from NEI (EY11754). Q.Z.: received grant support from NEI (EY11805, EY023263). W.H.: received grant support from NEI (EY11805) and also from NIDCR, USA (DE018886) for unrelated project. T.T.N.: received grant support from NEI (EY11756, EY11754). K.W.: received grant support from NEI (EY11754). K.D.: received grant support from NEI (EY022589) and from Quark Pharmaceuticals (USA) for an unrelated project. L.Z.: received grant support from NEI (EY022589), received equipment and materials from Optovue, Inc, Heidelberg Engineering, Zeiss Meditec, and Topcon. Funding/Support: This study was supported by the following National Eye Institute (United States) grants: EY11805 , EY023263, EY11740 , EY11756 , EY11754 , EY11752 , EY11755 , and P30EY022589 . The sponsor or funding organization had no role in the reporting or interpretation of study data. All authors attest that they meet the current ICMJE requirements to qualify as authors. Publisher Copyright: © 2015 BY ELSEVIER INC. ALL RIGHTS RESERVED.

PY - 2015/7/1

Y1 - 2015/7/1

N2 - Purpose To examine the relationship of choroidal thickness with axial length (AL) and myopia in young adult eyes in the ethnically diverse Correction of Myopia Evaluation Trial (COMET) cohort. Design Cross-sectional, multicenter study. Methods In addition to measures of myopia by cycloplegic autorefraction and AL by A-scan ultrasonography, participants underwent optical coherence tomography imaging of the choroid in both eyes at their last visit (14 years after baseline). Using digital calipers, 2 independent readers measured choroidal thickness in the right eye (left eye if poor quality; n = 37) at 7 locations: fovea and 750, 1500, and 2250 μm nasal (N) and temporal (T) to the fovea. Results Choroidal thickness measurements were available from 294 of 346 (85%) imaged participants (mean age: 24.3 ± 1.4 years; 44.9% male) with mean myopia of -5.3 ± 2.0 diopters and mean AL of 25.5 ± 1.0 mm. Overall, choroidal thickness varied by location (P <.0001) and was thickest at the fovea (273.8 ± 70.9 μm) and thinnest nasally (N2250, 191.5 ± 69.3 μm). Multivariable analyses showed significantly thinner choroids in eyes with more myopia and longer AL at all locations except T2250 (P ≤.001) and presence of peripapillary crescent at all locations except T1500 and T2250 (P ≤.0001). Choroidal thickness varied by ethnicity at N2250 (P <.0001), with Asians having the thinnest and African Americans the thickest choroids. Conclusion Choroids are thinner in longer, more myopic young adult eyes. The thinning was most prominent nasally and in eyes with a crescent. In the furthest nasal location, ethnicity was associated with choroidal thickness. The findings suggest that choroidal thickness should be evaluated, especially in the nasal regions where myopic degenerations are most commonly seen clinically.

AB - Purpose To examine the relationship of choroidal thickness with axial length (AL) and myopia in young adult eyes in the ethnically diverse Correction of Myopia Evaluation Trial (COMET) cohort. Design Cross-sectional, multicenter study. Methods In addition to measures of myopia by cycloplegic autorefraction and AL by A-scan ultrasonography, participants underwent optical coherence tomography imaging of the choroid in both eyes at their last visit (14 years after baseline). Using digital calipers, 2 independent readers measured choroidal thickness in the right eye (left eye if poor quality; n = 37) at 7 locations: fovea and 750, 1500, and 2250 μm nasal (N) and temporal (T) to the fovea. Results Choroidal thickness measurements were available from 294 of 346 (85%) imaged participants (mean age: 24.3 ± 1.4 years; 44.9% male) with mean myopia of -5.3 ± 2.0 diopters and mean AL of 25.5 ± 1.0 mm. Overall, choroidal thickness varied by location (P <.0001) and was thickest at the fovea (273.8 ± 70.9 μm) and thinnest nasally (N2250, 191.5 ± 69.3 μm). Multivariable analyses showed significantly thinner choroids in eyes with more myopia and longer AL at all locations except T2250 (P ≤.001) and presence of peripapillary crescent at all locations except T1500 and T2250 (P ≤.0001). Choroidal thickness varied by ethnicity at N2250 (P <.0001), with Asians having the thinnest and African Americans the thickest choroids. Conclusion Choroids are thinner in longer, more myopic young adult eyes. The thinning was most prominent nasally and in eyes with a crescent. In the furthest nasal location, ethnicity was associated with choroidal thickness. The findings suggest that choroidal thickness should be evaluated, especially in the nasal regions where myopic degenerations are most commonly seen clinically.

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U2 - 10.1016/j.ajo.2015.04.018

DO - 10.1016/j.ajo.2015.04.018

M3 - Article

C2 - 25896460

AN - SCOPUS:84930938788

SN - 0002-9394

VL - 160

SP - 62-71.e2

JO - American Journal of Ophthalmology

JF - American Journal of Ophthalmology

IS - 1

ER -

Choroidal thickness profiles in myopic eyes of young adults in the correction of myopia evaluation trial cohort

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