Choosing Performance-Based Outcome Measures of Daily Living Skills and Socialization for Clinical Trials in Autistic Children

Roseann C. Schaaf; Amy Carroll; Elizabeth Conte Waskie; Rachel L. Dumont; Elizabeth Ridgway

doi:10.5014/ajot.2021.044602

Choosing Performance-Based Outcome Measures of Daily Living Skills and Socialization for Clinical Trials in Autistic Children

Roseann C. Schaaf, Amy Carroll, Elizabeth Conte Waskie, Rachel L. Dumont, Elizabeth Ridgway

Pediatrics

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

IMPORTANCE: Robust and psychometrically sound performance-based outcome measures are needed for clinical trials of occupational therapy interventions for children with autism. OBJECTIVE: To demonstrate a systematic approach for choosing psychometrically sound performance-based outcome measures of daily living skills and socialization for use in clinical trials of occupational therapy interventions for children with autism. DESIGN: Rapid literature review to identify appropriate measures for studies with this population followed by quality indicator ratings and a nominal group process. SETTING: University. PARTICIPANTS: Four experts in autism and pediatric outcome measurement. Outcomes and Measures: Twenty-one outcome measures of daily living skills and socialization were identified and reviewed. RESULTS: Seven measures met the inclusion criteria. The Assessment of Motor and Process Skills and the Evaluation of Social Interaction-Second Edition, received the highest ratings and group consensus. Several other measures were also scored highly. CONCLUSIONS AND RELEVANCE: Careful assessment of psychometric properties is an important component of choosing outcome measures for a clinical trial, but burden of assessment and study objectives are important considerations. What This Article Adds: This project demonstrates use of a systematic process for choosing outcome measures for a planned clinical trial.

Original language	English (US)
Journal	American Journal of Occupational Therapy
Volume	75
Issue number	6
DOIs	https://doi.org/10.5014/ajot.2021.044602
State	Published - Nov 1 2021

ASJC Scopus subject areas

Occupational Therapy

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title = "Choosing Performance-Based Outcome Measures of Daily Living Skills and Socialization for Clinical Trials in Autistic Children",

abstract = "IMPORTANCE: Robust and psychometrically sound performance-based outcome measures are needed for clinical trials of occupational therapy interventions for children with autism. OBJECTIVE: To demonstrate a systematic approach for choosing psychometrically sound performance-based outcome measures of daily living skills and socialization for use in clinical trials of occupational therapy interventions for children with autism. DESIGN: Rapid literature review to identify appropriate measures for studies with this population followed by quality indicator ratings and a nominal group process. SETTING: University. PARTICIPANTS: Four experts in autism and pediatric outcome measurement. Outcomes and Measures: Twenty-one outcome measures of daily living skills and socialization were identified and reviewed. RESULTS: Seven measures met the inclusion criteria. The Assessment of Motor and Process Skills and the Evaluation of Social Interaction-Second Edition, received the highest ratings and group consensus. Several other measures were also scored highly. CONCLUSIONS AND RELEVANCE: Careful assessment of psychometric properties is an important component of choosing outcome measures for a clinical trial, but burden of assessment and study objectives are important considerations. What This Article Adds: This project demonstrates use of a systematic process for choosing outcome measures for a planned clinical trial.",

author = "Schaaf, {Roseann C.} and Amy Carroll and Waskie, {Elizabeth Conte} and Dumont, {Rachel L.} and Elizabeth Ridgway",

note = "Funding Information: This manuscript is dedicated to Ralph Mankovitz, who provided strong encouragement for early work in this field and articulated an original notion of isolating lectin-resistant membrane mutants. This work was supported by grants from the National Institutes of Health GM-21665 and Pol-Ca-26712 to R. M. B., CA-14151 to S. E. Luria, and CRIC-77015 and CA-17015 to C. B. H., who is a Faculty Research Awardee of the American Cancer Society. We thank L. A. Spencer, S. Lewis, and M. Perez for assistance with relevant laboratory work. Publisher Copyright: Copyright {\textcopyright} 2021 by the American Occupational Therapy Association, Inc.",

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AU - Dumont, Rachel L.

AU - Ridgway, Elizabeth

N1 - Funding Information: This manuscript is dedicated to Ralph Mankovitz, who provided strong encouragement for early work in this field and articulated an original notion of isolating lectin-resistant membrane mutants. This work was supported by grants from the National Institutes of Health GM-21665 and Pol-Ca-26712 to R. M. B., CA-14151 to S. E. Luria, and CRIC-77015 and CA-17015 to C. B. H., who is a Faculty Research Awardee of the American Cancer Society. We thank L. A. Spencer, S. Lewis, and M. Perez for assistance with relevant laboratory work. Publisher Copyright: Copyright © 2021 by the American Occupational Therapy Association, Inc.

PY - 2021/11/1

Y1 - 2021/11/1

N2 - IMPORTANCE: Robust and psychometrically sound performance-based outcome measures are needed for clinical trials of occupational therapy interventions for children with autism. OBJECTIVE: To demonstrate a systematic approach for choosing psychometrically sound performance-based outcome measures of daily living skills and socialization for use in clinical trials of occupational therapy interventions for children with autism. DESIGN: Rapid literature review to identify appropriate measures for studies with this population followed by quality indicator ratings and a nominal group process. SETTING: University. PARTICIPANTS: Four experts in autism and pediatric outcome measurement. Outcomes and Measures: Twenty-one outcome measures of daily living skills and socialization were identified and reviewed. RESULTS: Seven measures met the inclusion criteria. The Assessment of Motor and Process Skills and the Evaluation of Social Interaction-Second Edition, received the highest ratings and group consensus. Several other measures were also scored highly. CONCLUSIONS AND RELEVANCE: Careful assessment of psychometric properties is an important component of choosing outcome measures for a clinical trial, but burden of assessment and study objectives are important considerations. What This Article Adds: This project demonstrates use of a systematic process for choosing outcome measures for a planned clinical trial.

AB - IMPORTANCE: Robust and psychometrically sound performance-based outcome measures are needed for clinical trials of occupational therapy interventions for children with autism. OBJECTIVE: To demonstrate a systematic approach for choosing psychometrically sound performance-based outcome measures of daily living skills and socialization for use in clinical trials of occupational therapy interventions for children with autism. DESIGN: Rapid literature review to identify appropriate measures for studies with this population followed by quality indicator ratings and a nominal group process. SETTING: University. PARTICIPANTS: Four experts in autism and pediatric outcome measurement. Outcomes and Measures: Twenty-one outcome measures of daily living skills and socialization were identified and reviewed. RESULTS: Seven measures met the inclusion criteria. The Assessment of Motor and Process Skills and the Evaluation of Social Interaction-Second Edition, received the highest ratings and group consensus. Several other measures were also scored highly. CONCLUSIONS AND RELEVANCE: Careful assessment of psychometric properties is an important component of choosing outcome measures for a clinical trial, but burden of assessment and study objectives are important considerations. What This Article Adds: This project demonstrates use of a systematic process for choosing outcome measures for a planned clinical trial.

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Choosing Performance-Based Outcome Measures of Daily Living Skills and Socialization for Clinical Trials in Autistic Children

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