Chemotherapy of vulvar cancer: A review

Gunter Deppe, Ismail Mert, Jimmy Belotte, Ira S. Winer

Research output: Contribution to journalReview article

7 Scopus citations

Abstract

Squamous cell carcinoma of the vulva is a rare disease with good prognosis if diagnosed early. The standard primary therapy is surgery. Neoadjuvant radiation or chemotherapy has been used to achieve resectability of the tumor and to decrease the radicality of the surgery. Chemotherapy with platinum compounds, paclitaxel and targeted therapy (erlotinib) has shown activity. International collaborative trials are needed to identify the best therapeutic strategy for patients with squamous cell cancer of the vulva who are not candidates for primary surgery or concomitant chemoradiation. We review the various treatment options available to patients with advanced or recurrent squamous cell cancer of the vulva.

Original languageEnglish (US)
Pages (from-to)119-128
Number of pages10
JournalWiener Klinische Wochenschrift
Volume125
Issue number5-6
DOIs
StatePublished - Mar 1 2013

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Keywords

  • Chemotherapy
  • Vulvar cancer

ASJC Scopus subject areas

  • Medicine(all)

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