Eighteen patients with measurable or evaluable lesions from squamous cancer of the esophagus received a regimen combining four active agents on an outpatient basis. Nine of 14 evaluable patients (64%, or 50% of 18 patients entered) responded: four of five with previously untreated regional disease and five of nine with recurrent or metastatic disease. Median duration of response in the latter group was 5 months (longest response, 13). Treatment was well-tolerated in all patients but one, who developed signs of severe methotrexate toxicity and died of sepsis.
|Original language||English (US)|
|Number of pages||3|
|Journal||Cancer Treatment Reports|
|Publication status||Published - Jan 1 1985|
ASJC Scopus subject areas
- Cancer Research