Chemical crosslinking of the mononuclear phagocyte specific growth factor CSF-1 to its receptor at the cell surface

Claudia J. Morgan, E. Richard Stanley

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

The cell surface receptor for CSF-1 has been identified by affinity labeling intact mouse bone marrow-derived macrophages and intact cells of the murine J774.2 and BAC1 lines, which differ in their specific CSF-1 binding capacities and biological responses. The receptor, labeled by crosslinking to 125I-CSF-1 with disuccinimidyl suberate, is a polypeptide of approximately 165,000 molecular weight, irrespective of cell type.

Original languageEnglish (US)
Pages (from-to)35-41
Number of pages7
JournalBiochemical and Biophysical Research Communications
Volume119
Issue number1
DOIs
StatePublished - Feb 29 1984

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

Fingerprint Dive into the research topics of 'Chemical crosslinking of the mononuclear phagocyte specific growth factor CSF-1 to its receptor at the cell surface'. Together they form a unique fingerprint.

  • Cite this