Characterization of cognitive functioning in a subgroup of children with congenital HIV infection

Gary W. Diamond, Judith Kaufman, Anita L. Belman, Lucy Cohen, Herbert J. Cohen, Arye Rubinstein

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

The cognitive status of 12 clinically stable children with congenital HIV infection, nine of whom were neurologically impaired, age three to nine years, was assessed using the Kaufman ABC test. Seven of the children had ARC; five were diagnosed as having AIDS. The same children were evaluated by standard neurologic examinations with Characterization of tone and fine motor functioning. Two were diagnosed as being mildly retarded; six were borderline; and four tested as being of average intelligence. Visual-spatial perceptual based functioning was found to be more impaired than were abstract reasoning and verbally mediated skills in six (50%) of the patients. This pattern of impaired information processing was found irrespective of overall cognitive status. On neurological and physiatric examination abnormal developmental histories were obtained, or poor fine motor coordination, abnormal tone and gait, and impaired rapidly alternating movements were found in 9 of the 12 subjects. These findings suggest selective impairment in distinct areas of neurologic and neuropsychological functioning during stable phases of H1V infection in a select group of children. These patterns appear to persist over time. They differ from the clustering of impaired skills seen in children of comparable socio-cultural backgrounds without HIV infection. Similarities in functioning are noted between this subgroup of children with AIDS and ARC and comparable groups with cerebral palsy.

Original languageEnglish (US)
Pages (from-to)245-256
Number of pages12
JournalArchives of Clinical Neuropsychology
Volume2
Issue number3
DOIs
StatePublished - 1987

Fingerprint

HIV Infections
AIDS-Related Complex
Neurologic Examination
Acquired Immunodeficiency Syndrome
Physical and Rehabilitation Medicine
Cerebral Palsy
Intelligence
Automatic Data Processing
Gait
Nervous System
Cluster Analysis
Infection

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Psychology
  • Neuropsychology and Physiological Psychology

Cite this

Characterization of cognitive functioning in a subgroup of children with congenital HIV infection. / Diamond, Gary W.; Kaufman, Judith; Belman, Anita L.; Cohen, Lucy; Cohen, Herbert J.; Rubinstein, Arye.

In: Archives of Clinical Neuropsychology, Vol. 2, No. 3, 1987, p. 245-256.

Research output: Contribution to journalArticle

Diamond, Gary W. ; Kaufman, Judith ; Belman, Anita L. ; Cohen, Lucy ; Cohen, Herbert J. ; Rubinstein, Arye. / Characterization of cognitive functioning in a subgroup of children with congenital HIV infection. In: Archives of Clinical Neuropsychology. 1987 ; Vol. 2, No. 3. pp. 245-256.
@article{9eaec8b613b2445b8c56891833f2fe6f,
title = "Characterization of cognitive functioning in a subgroup of children with congenital HIV infection",
abstract = "The cognitive status of 12 clinically stable children with congenital HIV infection, nine of whom were neurologically impaired, age three to nine years, was assessed using the Kaufman ABC test. Seven of the children had ARC; five were diagnosed as having AIDS. The same children were evaluated by standard neurologic examinations with Characterization of tone and fine motor functioning. Two were diagnosed as being mildly retarded; six were borderline; and four tested as being of average intelligence. Visual-spatial perceptual based functioning was found to be more impaired than were abstract reasoning and verbally mediated skills in six (50{\%}) of the patients. This pattern of impaired information processing was found irrespective of overall cognitive status. On neurological and physiatric examination abnormal developmental histories were obtained, or poor fine motor coordination, abnormal tone and gait, and impaired rapidly alternating movements were found in 9 of the 12 subjects. These findings suggest selective impairment in distinct areas of neurologic and neuropsychological functioning during stable phases of H1V infection in a select group of children. These patterns appear to persist over time. They differ from the clustering of impaired skills seen in children of comparable socio-cultural backgrounds without HIV infection. Similarities in functioning are noted between this subgroup of children with AIDS and ARC and comparable groups with cerebral palsy.",
author = "Diamond, {Gary W.} and Judith Kaufman and Belman, {Anita L.} and Lucy Cohen and Cohen, {Herbert J.} and Arye Rubinstein",
year = "1987",
doi = "10.1016/0887-6177(87)90012-6",
language = "English (US)",
volume = "2",
pages = "245--256",
journal = "Archives of Clinical Neuropsychology",
issn = "1873-5843",
publisher = "Elsevier BV",
number = "3",

}

TY - JOUR

T1 - Characterization of cognitive functioning in a subgroup of children with congenital HIV infection

AU - Diamond, Gary W.

AU - Kaufman, Judith

AU - Belman, Anita L.

AU - Cohen, Lucy

AU - Cohen, Herbert J.

AU - Rubinstein, Arye

PY - 1987

Y1 - 1987

N2 - The cognitive status of 12 clinically stable children with congenital HIV infection, nine of whom were neurologically impaired, age three to nine years, was assessed using the Kaufman ABC test. Seven of the children had ARC; five were diagnosed as having AIDS. The same children were evaluated by standard neurologic examinations with Characterization of tone and fine motor functioning. Two were diagnosed as being mildly retarded; six were borderline; and four tested as being of average intelligence. Visual-spatial perceptual based functioning was found to be more impaired than were abstract reasoning and verbally mediated skills in six (50%) of the patients. This pattern of impaired information processing was found irrespective of overall cognitive status. On neurological and physiatric examination abnormal developmental histories were obtained, or poor fine motor coordination, abnormal tone and gait, and impaired rapidly alternating movements were found in 9 of the 12 subjects. These findings suggest selective impairment in distinct areas of neurologic and neuropsychological functioning during stable phases of H1V infection in a select group of children. These patterns appear to persist over time. They differ from the clustering of impaired skills seen in children of comparable socio-cultural backgrounds without HIV infection. Similarities in functioning are noted between this subgroup of children with AIDS and ARC and comparable groups with cerebral palsy.

AB - The cognitive status of 12 clinically stable children with congenital HIV infection, nine of whom were neurologically impaired, age three to nine years, was assessed using the Kaufman ABC test. Seven of the children had ARC; five were diagnosed as having AIDS. The same children were evaluated by standard neurologic examinations with Characterization of tone and fine motor functioning. Two were diagnosed as being mildly retarded; six were borderline; and four tested as being of average intelligence. Visual-spatial perceptual based functioning was found to be more impaired than were abstract reasoning and verbally mediated skills in six (50%) of the patients. This pattern of impaired information processing was found irrespective of overall cognitive status. On neurological and physiatric examination abnormal developmental histories were obtained, or poor fine motor coordination, abnormal tone and gait, and impaired rapidly alternating movements were found in 9 of the 12 subjects. These findings suggest selective impairment in distinct areas of neurologic and neuropsychological functioning during stable phases of H1V infection in a select group of children. These patterns appear to persist over time. They differ from the clustering of impaired skills seen in children of comparable socio-cultural backgrounds without HIV infection. Similarities in functioning are noted between this subgroup of children with AIDS and ARC and comparable groups with cerebral palsy.

UR - http://www.scopus.com/inward/record.url?scp=0023627994&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023627994&partnerID=8YFLogxK

U2 - 10.1016/0887-6177(87)90012-6

DO - 10.1016/0887-6177(87)90012-6

M3 - Article

C2 - 14589616

AN - SCOPUS:0023627994

VL - 2

SP - 245

EP - 256

JO - Archives of Clinical Neuropsychology

JF - Archives of Clinical Neuropsychology

SN - 1873-5843

IS - 3

ER -