Chaperone-mediated autophagy

Dice's 'wild' idea about lysosomal selectivity

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

A little over 1 year ago, we lost a bright scientist and a dear colleague who, in his younger years, proposed the 'heretical' idea that lysosomes could selectively degrade cytosolic proteins. That scientist was J. Fred Dice, and his lifetime's discovery was the degradative pathway that we now know as chaperone-mediated autophagy.

Original languageEnglish (US)
Pages (from-to)535-541
Number of pages7
JournalNature Reviews Molecular Cell Biology
Volume12
Issue number8
DOIs
StatePublished - Aug 2011

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Autophagy
Lysosomes
Proteins

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

Cite this

Chaperone-mediated autophagy : Dice's 'wild' idea about lysosomal selectivity. / Cuervo, Ana Maria.

In: Nature Reviews Molecular Cell Biology, Vol. 12, No. 8, 08.2011, p. 535-541.

Research output: Contribution to journalArticle

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