Channeling the homocysteine chapel

Research output: Contribution to journalComment/debate

3 Scopus citations

Abstract

Hyperhomocysteinemia (HHcy), a potent risk factor for cardiovascular disease, is associated with impaired endothelium-dependent vasodilation. In this issue of Blood, Cheng et al report that severe HHcy causes oxidation and tyrosine nitration of small and intermediate conductance Ca2+-activated potassium channels, resulting in impaired endothelium-derived hyperpolarizing factor (EDHF)-mediated relaxation of resistance arterioles.1.

Original languageEnglish (US)
Pages (from-to)1717-1719
Number of pages3
JournalBlood
Volume118
Issue number7
DOIs
StatePublished - Aug 18 2011

ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

Fingerprint Dive into the research topics of 'Channeling the homocysteine chapel'. Together they form a unique fingerprint.

  • Cite this