TY - JOUR
T1 - Changes in knowledge of cervical cancer following introduction of human papillomavirus vaccine among women at high risk for cervical cancer
AU - Stewart Massad, L.
AU - Evans, Charlesnika T.
AU - Weber, Kathleen M.
AU - D'Souza, Gypsyamber
AU - Hessol, Nancy A.
AU - Wright, Rodney L.
AU - Colie, Christine
AU - Strickler, Howard D.
AU - Wilson, Tracey E.
N1 - Funding Information:
Data in this manuscript were collected by the Women's Interagency HIV Study (WIHS). The contents of this publication are solely the responsibility of the authors and do not represent the official views of the National Institutes of Health (NIH). WIHS (Principal Investigators): Bronx WIHS (Kathryn Anastos), U01-AI-035004; Brooklyn WIHS (Howard Minkoff and Deborah Gustafson), U01-AI-031834; Chicago WIHS (Mardge Cohen), U01-AI-034993; Metropolitan Washington WIHS (Mary Young), U01-AI-034994; Connie Wofsy Women's HIV Study, Northern California (Ruth Greenblatt, Bradley Aouizerat, and Phyllis Tien), U01-AI-034989; WIHS Data Management and Analysis Center (Stephen Gange and Elizabeth Golub), U01-AI-042590; Southern California WIHS (Joel Milam), U01-HD-032632 (WIHS I–WIHS IV). The WIHS is funded primarily by the National Institute of Allergy and Infectious Diseases (NIAID) , with additional co-funding from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) , the National Cancer Institute (NCI) , the National Institute on Drug Abuse (NIDA) , and the National Institute on Mental Health (NIMH) . Targeted supplemental funding for specific projects is also provided by the National Institute of Dental and Craniofacial Research (NIDCR) , the National Institute on Alcohol Abuse and Alcoholism (NIAAA) , the National Institute on Deafness and other Communication Disorders (NIDCD) , and the NIH Office of Research on Women's Health. WIHS data collection is also supported by UL1-TR000004 (UCSF CTSA).
Publisher Copyright:
© 2015 The Authors. Published by Elsevier Inc.
PY - 2015/4/1
Y1 - 2015/4/1
N2 - Purpose: To describe changes in knowledge of cervical cancer prevention, human papillomavirus (HPV), and HPV vaccination among women at high risk for cervical cancer in the first five years after introduction of HPV vaccination. Methods: In 2007, 2008-9, and 2011, women in a multicenter U.S. cohort study completed 44-item self-report questionnaires assessing knowledge of cervical cancer prevention, HPV, and HPV vaccination. Results across time were assessed for individuals, and three study enrollment cohorts were compared. Knowledge scores were correlated with demographic variables, measures of education and attention, and medical factors. Associations were assessed in multivariable models. Results: In all, 974 women completed three serial questionnaires; most were minority, low income, and current or former smokers. The group included 652 (67%) HIV infected and 322 (33%) uninfected. Summary knowledge scores (possible range 0-24) increased from 2007 (12.8, S.D. 5.8) to 2008-9 (13.9, S.D. 5.3, P < 0.001) and to 2011 (14.3, S.D. 5.2, P < 0.0001 vs 2007 and < 0.04 vs 2008-9). Higher knowledge scores at first and follow-up administration of questionnaires, higher income, and higher education level were associated with improved knowledge score at third administration. Women not previously surveyed had scores similar to those of the longitudinal group at baseline. Conclusion: Substantial gaps in understanding of HPV and cervical cancer prevention exist despite years of health education. While more effective educational interventions may help, optimal cancer prevention may require opt-out vaccination programs that do not require nuanced understanding.
AB - Purpose: To describe changes in knowledge of cervical cancer prevention, human papillomavirus (HPV), and HPV vaccination among women at high risk for cervical cancer in the first five years after introduction of HPV vaccination. Methods: In 2007, 2008-9, and 2011, women in a multicenter U.S. cohort study completed 44-item self-report questionnaires assessing knowledge of cervical cancer prevention, HPV, and HPV vaccination. Results across time were assessed for individuals, and three study enrollment cohorts were compared. Knowledge scores were correlated with demographic variables, measures of education and attention, and medical factors. Associations were assessed in multivariable models. Results: In all, 974 women completed three serial questionnaires; most were minority, low income, and current or former smokers. The group included 652 (67%) HIV infected and 322 (33%) uninfected. Summary knowledge scores (possible range 0-24) increased from 2007 (12.8, S.D. 5.8) to 2008-9 (13.9, S.D. 5.3, P < 0.001) and to 2011 (14.3, S.D. 5.2, P < 0.0001 vs 2007 and < 0.04 vs 2008-9). Higher knowledge scores at first and follow-up administration of questionnaires, higher income, and higher education level were associated with improved knowledge score at third administration. Women not previously surveyed had scores similar to those of the longitudinal group at baseline. Conclusion: Substantial gaps in understanding of HPV and cervical cancer prevention exist despite years of health education. While more effective educational interventions may help, optimal cancer prevention may require opt-out vaccination programs that do not require nuanced understanding.
KW - Cervical cancer prevention
KW - Health education
KW - Human immunodeficiency virus in women
KW - Human papillomavirus
KW - Pap test
UR - http://www.scopus.com/inward/record.url?scp=84964860918&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84964860918&partnerID=8YFLogxK
U2 - 10.1016/j.gore.2015.02.007
DO - 10.1016/j.gore.2015.02.007
M3 - Article
AN - SCOPUS:84964860918
SN - 2211-338X
VL - 12
SP - 37
EP - 40
JO - Gynecologic Oncology Case Reports
JF - Gynecologic Oncology Case Reports
ER -
