Cervicovaginal human papillomavirus infection in suburban adolescents and young adults

Martin Fisher, Walter D. Rosenfeld, Robert D. Burk

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

To investigate the prevalence rates of and risk factors for genital human papillomavirus (HPV) infection in white, middle-class adolescents, we obtained specimens for HPV from 107 patients undergoing pelvic examination at a suburban adolescent health service. Specimens were obtained by means of cervicovaginal lavage and were analyzed for HPV DNA by Southern blot analysis. The subjects' mean age was 18.5 (±2.0 SD) years; 47% of the subjects were seen for contraception, 36% for possible pregnancy, 12% for a gynecologic complaint, and 5% for a general examination. We detected HPV in 32% of patients; HPV types included 6/11 (6%), 16 (3%), 18 (15%), 31 (3%), 42 (6%), 45 (18%), and 56 (6%). The DNA type was classified as uncharacterized in 47%, and 3% had more than one type. Univariate analysis revealed that patients found to have HPV were more likely to have more than two sexual partners, to have been sexually active for more than 2 years, to have had menarche before 12 years of age, and to have a history of sexually transmitted disease; logistic regression multivariate analysis demonstrated that number of partners and age at menarche were independent risk factors for HPV. These data indicate that HPV is common among sexually active teenagers regardless of ethnicity or socioeconomic status. The association of cervicovaginal HPV infection with sexual activity further supports the notion of the sexual transmission of this agent.

Original languageEnglish (US)
Pages (from-to)821-825
Number of pages5
JournalThe Journal of Pediatrics
Volume119
Issue number5
DOIs
StatePublished - 1991

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Papillomavirus Infections
Young Adult
Menarche
Suburban Health Services
Adolescent Health Services
Human papillomavirus 6
Gynecological Examination
Sexual Partners
Therapeutic Irrigation
DNA
Sexually Transmitted Diseases
Southern Blotting
Contraception
Social Class
Sexual Behavior
Multivariate Analysis
Logistic Models
Regression Analysis
Pregnancy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Cervicovaginal human papillomavirus infection in suburban adolescents and young adults. / Fisher, Martin; Rosenfeld, Walter D.; Burk, Robert D.

In: The Journal of Pediatrics, Vol. 119, No. 5, 1991, p. 821-825.

Research output: Contribution to journalArticle

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