Cerebral lesions in congenital rubella syndrome

Lucy Balian Rorke, Alfred J. Spiro

Research output: Contribution to journalArticle

78 Citations (Scopus)

Abstract

Study of the brains of 9 infants less than 1 year of age with congenital rubella syndrome revealed extensive degenerative changes in leptomeningeal and intrinsic arteries and veins of the cerebrum. Vascular damage was associated with foci of necrosis localized chiefly in the deep white matter and gray nuclei. There was retardation in myelinization of selected neural systems in 5 of 8 infants surviving for more than one month. No developmental malformations or significant inflammation of the nervous system was found in the group.

Original languageEnglish (US)
JournalThe Journal of Pediatrics
Volume70
Issue number2
StatePublished - Feb 1967
Externally publishedYes

Fingerprint

Congenital Rubella Syndrome
Cerebrum
Nervous System
Blood Vessels
Veins
Necrosis
Arteries
Inflammation
Brain

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Rorke, L. B., & Spiro, A. J. (1967). Cerebral lesions in congenital rubella syndrome. The Journal of Pediatrics, 70(2).

Cerebral lesions in congenital rubella syndrome. / Rorke, Lucy Balian; Spiro, Alfred J.

In: The Journal of Pediatrics, Vol. 70, No. 2, 02.1967.

Research output: Contribution to journalArticle

Rorke, LB & Spiro, AJ 1967, 'Cerebral lesions in congenital rubella syndrome', The Journal of Pediatrics, vol. 70, no. 2.
Rorke, Lucy Balian ; Spiro, Alfred J. / Cerebral lesions in congenital rubella syndrome. In: The Journal of Pediatrics. 1967 ; Vol. 70, No. 2.
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