Central pain from cerebral abscess: Thalamic syndrome in aids patients with toxoplasmosis

Gilbert R. Gonzales, Steven Herskovitz, M. Rosenblum, K. M. Foley, R. Kanner, A. Brown, R. K. Portenoy

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

We describe two patients with acquired immunodeficiency syndrome (AIDS) who developed classic thalamic syndrome (TS) due to Toxoplasma abscesses in the thalamic region. Treatment with amitriptyline provided substantial relief in both patients. Postmortem examination in one case revealed a lesion in the internal capsule and thalamic reticular nucleus. These observations indicate that (1) TS can result from an isolated lesion in the internal capsule and reticular nucleus of the thalamus, (2) cerebral abscess can cause classic TS, (3) central pain can be added to the many pain syndromes that afflict AIDS patients, and (4) an analgesic response to amitriptyline is possible in these patients.

Original languageEnglish (US)
Pages (from-to)1107-1109
Number of pages3
JournalNeurology
Volume42
Issue number5
StatePublished - 1992

Fingerprint

Thalamic Diseases
Brain Abscess
Toxoplasmosis
Internal Capsule
Pain
Amitriptyline
Acquired Immunodeficiency Syndrome
Thalamic Nuclei
Toxoplasma
Thalamus
Abscess
Analgesics
Autopsy
Syndrome

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Gonzales, G. R., Herskovitz, S., Rosenblum, M., Foley, K. M., Kanner, R., Brown, A., & Portenoy, R. K. (1992). Central pain from cerebral abscess: Thalamic syndrome in aids patients with toxoplasmosis. Neurology, 42(5), 1107-1109.

Central pain from cerebral abscess : Thalamic syndrome in aids patients with toxoplasmosis. / Gonzales, Gilbert R.; Herskovitz, Steven; Rosenblum, M.; Foley, K. M.; Kanner, R.; Brown, A.; Portenoy, R. K.

In: Neurology, Vol. 42, No. 5, 1992, p. 1107-1109.

Research output: Contribution to journalArticle

Gonzales, GR, Herskovitz, S, Rosenblum, M, Foley, KM, Kanner, R, Brown, A & Portenoy, RK 1992, 'Central pain from cerebral abscess: Thalamic syndrome in aids patients with toxoplasmosis', Neurology, vol. 42, no. 5, pp. 1107-1109.
Gonzales GR, Herskovitz S, Rosenblum M, Foley KM, Kanner R, Brown A et al. Central pain from cerebral abscess: Thalamic syndrome in aids patients with toxoplasmosis. Neurology. 1992;42(5):1107-1109.
Gonzales, Gilbert R. ; Herskovitz, Steven ; Rosenblum, M. ; Foley, K. M. ; Kanner, R. ; Brown, A. ; Portenoy, R. K. / Central pain from cerebral abscess : Thalamic syndrome in aids patients with toxoplasmosis. In: Neurology. 1992 ; Vol. 42, No. 5. pp. 1107-1109.
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