Central pain from cerebral abscess: Thalamic syndrome in aids patients with toxoplasmosis

Gilbert R. Gonzales, S. Herskovitz, M. Rosenblum, K. M. Foley, R. Kanner, A. Brown, R. K. Portenoy

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Abstract

We describe two patients with acquired immunodeficiency syndrome (AIDS) who developed classic thalamic syndrome (TS) due to Toxoplasma abscesses in the thalamic region. Treatment with amitriptyline provided substantial relief in both patients. Postmortem examination in one case revealed a lesion in the internal capsule and thalamic reticular nucleus. These observations indicate that (1) TS can result from an isolated lesion in the internal capsule and reticular nucleus of the thalamus, (2) cerebral abscess can cause classic TS, (3) central pain can be added to the many pain syndromes that afflict AIDS patients, and (4) an analgesic response to amitriptyline is possible in these patients.

Original languageEnglish (US)
Pages (from-to)1107-1109
Number of pages3
JournalNeurology
Volume42
Issue number5
Publication statusPublished - May 1992

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ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Gonzales, G. R., Herskovitz, S., Rosenblum, M., Foley, K. M., Kanner, R., Brown, A., & Portenoy, R. K. (1992). Central pain from cerebral abscess: Thalamic syndrome in aids patients with toxoplasmosis. Neurology, 42(5), 1107-1109.