Central neurocytoma responsive to topotecan, ifosfamide, carboplatin

Elham Amini, Tina Roffidal, Alice Lee, Gregory N. Fuller, Anita Mahajan, Leena Ketonen, Nathan Kobrinsky, Mitchell S. Cairo, Robert J. Wells, Johannes E.A. Wolff

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

A 5-year-old male presented with spinal cord drop metastasis from a recurrent neurocytoma. Topotecan (0.5 mg/m2) and carboplatin (250 mg/m2) were administered on days 1-3 and ifosfamide (1,800 mg/m 2) on days 1-5, every 21 days, for three cycles and resulted in complete response without severe complications. A literature review yielded 20 patients with central neurocytoma but no complete responses. The complete response of central neurocytoma to chemotherapy only reported here should be helpful to those caring for patients with this rare tumor.

Original languageEnglish (US)
Pages (from-to)137-140
Number of pages4
JournalPediatric Blood and Cancer
Volume51
Issue number1
DOIs
StatePublished - Jul 2008
Externally publishedYes

Keywords

  • Chemotherapy
  • Neurocytoma
  • Pediatric

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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