Central nervous system manifestations of Angiostrongylus cantonensis infection

Yuri C. Martins, Herbert B. Tanowitz, Kevin R. Kazacos

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Over 20 species of Angiostrongylus have been described from around the world, but only Angiostrongylus cantonensis has been confirmed to cause central nervous system disease in humans. A neurotropic parasite that matures in the pulmonary arteries of rats, A. cantonensis is the most common cause of eosinophilic meningitis in southern Asia and the Pacific and Caribbean islands. The parasite can also cause encephalitis/encephalomyelitis and rarely ocular angiostrongyliasis. The present paper reviews the life cycle, epidemiology, pathogenesis, clinical features, diagnosis, treatment, prevention and prognosis of A. cantonesis infection. Emphasis is given on the spectrum of central nervous system manifestations and disease pathogenesis.

Original languageEnglish (US)
Pages (from-to)46-53
Number of pages8
JournalActa Tropica
Issue numberPart A
DOIs
StatePublished - Jan 1 2015

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Angiostrongylus cantonensis
Parastrongylus cantonensis
Central Nervous System Diseases
encephalitis
central nervous system
Parasites
Angiostrongylus
pathogenesis
Central Nervous System
Pacific Islands
West Indies
Encephalomyelitis
parasites
central nervous system diseases
pulmonary artery
meningitis
Encephalitis
Infection
Life Cycle Stages
Meningitis

Keywords

  • Angiostrongylus cantonensis
  • Eosinophilic meningitis
  • Parasitic encephalitis

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Central nervous system manifestations of Angiostrongylus cantonensis infection. / Martins, Yuri C.; Tanowitz, Herbert B.; Kazacos, Kevin R.

In: Acta Tropica, No. Part A, 01.01.2015, p. 46-53.

Research output: Contribution to journalArticle

Martins, Yuri C. ; Tanowitz, Herbert B. ; Kazacos, Kevin R. / Central nervous system manifestations of Angiostrongylus cantonensis infection. In: Acta Tropica. 2015 ; No. Part A. pp. 46-53.
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