TY - JOUR
T1 - Central Gustatory Lesions
T2 - I. Preference and Taste Reactivity Tests
AU - Flynn, Francis W.
AU - Grill, Harvey J.
AU - Schwartz, Gary J.
AU - Norgren, Ralph
PY - 1991/12
Y1 - 1991/12
N2 - Bilateral electrophysiologically guided lesions were placed in the nucleus of the solitary tract (NST), the parabrachial nucleus (PBN), and the ventral posteromedial thalamic nucleus (VPMpc) of rats, and 15-min intake and taste reactivity (TR) responses elicited by 3 concentrations each of sucrose, NaCI, HCI, and quinine (Q) HCI were subsequently measured. Compared with controls, NST lesions had no significant effects on intake, and rats with PBN lesions consumed significantly more QHCI, sucrose, NaCI, and HCI. Thalamic lesions decreased sucrose intake. Analysis of TR responses showed that the QHCI threshold for aversive responses increased after VPMpc, PBN, and NST lesions. Rats with NST or PBN lesions were unresponsive to increasing sucrose concentration. TR responses elicited by NaCI and HCI were similar across the groups.
AB - Bilateral electrophysiologically guided lesions were placed in the nucleus of the solitary tract (NST), the parabrachial nucleus (PBN), and the ventral posteromedial thalamic nucleus (VPMpc) of rats, and 15-min intake and taste reactivity (TR) responses elicited by 3 concentrations each of sucrose, NaCI, HCI, and quinine (Q) HCI were subsequently measured. Compared with controls, NST lesions had no significant effects on intake, and rats with PBN lesions consumed significantly more QHCI, sucrose, NaCI, and HCI. Thalamic lesions decreased sucrose intake. Analysis of TR responses showed that the QHCI threshold for aversive responses increased after VPMpc, PBN, and NST lesions. Rats with NST or PBN lesions were unresponsive to increasing sucrose concentration. TR responses elicited by NaCI and HCI were similar across the groups.
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U2 - 10.1037/0735-7044.105.6.933
DO - 10.1037/0735-7044.105.6.933
M3 - Article
C2 - 1663764
AN - SCOPUS:0026005528
SN - 0735-7044
VL - 105
SP - 933
EP - 943
JO - Behavioral Neuroscience
JF - Behavioral Neuroscience
IS - 6
ER -