Cell competition and its possible relation to cancer

Research output: Contribution to journalArticle

57 Citations (Scopus)

Abstract

Cell competition can occur when cells of different genotypes share the same developing compartment, with one genotype displacing the other as a result of a proliferative advantage. Studies of cell competition in Drosophila have identified an active process of cell assassination and corpse engulfment, and also roles for Myc and the Warts/Hippo tumor suppressor pathway. Here, we discuss the possible relevance of cell competition to cancer.

Original languageEnglish (US)
Pages (from-to)5505-5507
Number of pages3
JournalCancer Research
Volume68
Issue number14
DOIs
StatePublished - Jul 15 2008

Fingerprint

Neoplasms
Genotype
Warts
Cadaver
Drosophila

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Cell competition and its possible relation to cancer. / Baker, Nicholas E.; Li, Wei.

In: Cancer Research, Vol. 68, No. 14, 15.07.2008, p. 5505-5507.

Research output: Contribution to journalArticle

Baker, Nicholas E. ; Li, Wei. / Cell competition and its possible relation to cancer. In: Cancer Research. 2008 ; Vol. 68, No. 14. pp. 5505-5507.
@article{7d78c0e8d0844f3e802e283c5a63a8b0,
title = "Cell competition and its possible relation to cancer",
abstract = "Cell competition can occur when cells of different genotypes share the same developing compartment, with one genotype displacing the other as a result of a proliferative advantage. Studies of cell competition in Drosophila have identified an active process of cell assassination and corpse engulfment, and also roles for Myc and the Warts/Hippo tumor suppressor pathway. Here, we discuss the possible relevance of cell competition to cancer.",
author = "Baker, {Nicholas E.} and Wei Li",
year = "2008",
month = "7",
day = "15",
doi = "10.1158/0008-5472.CAN-07-6348",
language = "English (US)",
volume = "68",
pages = "5505--5507",
journal = "Cancer Research",
issn = "0008-5472",
publisher = "American Association for Cancer Research Inc.",
number = "14",

}

TY - JOUR

T1 - Cell competition and its possible relation to cancer

AU - Baker, Nicholas E.

AU - Li, Wei

PY - 2008/7/15

Y1 - 2008/7/15

N2 - Cell competition can occur when cells of different genotypes share the same developing compartment, with one genotype displacing the other as a result of a proliferative advantage. Studies of cell competition in Drosophila have identified an active process of cell assassination and corpse engulfment, and also roles for Myc and the Warts/Hippo tumor suppressor pathway. Here, we discuss the possible relevance of cell competition to cancer.

AB - Cell competition can occur when cells of different genotypes share the same developing compartment, with one genotype displacing the other as a result of a proliferative advantage. Studies of cell competition in Drosophila have identified an active process of cell assassination and corpse engulfment, and also roles for Myc and the Warts/Hippo tumor suppressor pathway. Here, we discuss the possible relevance of cell competition to cancer.

UR - http://www.scopus.com/inward/record.url?scp=48649094457&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=48649094457&partnerID=8YFLogxK

U2 - 10.1158/0008-5472.CAN-07-6348

DO - 10.1158/0008-5472.CAN-07-6348

M3 - Article

VL - 68

SP - 5505

EP - 5507

JO - Cancer Research

JF - Cancer Research

SN - 0008-5472

IS - 14

ER -