Cell competition and its possible relation to cancer

Research output: Contribution to journalReview article

59 Scopus citations

Abstract

Cell competition can occur when cells of different genotypes share the same developing compartment, with one genotype displacing the other as a result of a proliferative advantage. Studies of cell competition in Drosophila have identified an active process of cell assassination and corpse engulfment, and also roles for Myc and the Warts/Hippo tumor suppressor pathway. Here, we discuss the possible relevance of cell competition to cancer.

Original languageEnglish (US)
Pages (from-to)5505-5507
Number of pages3
JournalCancer Research
Volume68
Issue number14
DOIs
StatePublished - Jul 15 2008

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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