Cell competition can occur when cells of different genotypes share the same developing compartment, with one genotype displacing the other as a result of a proliferative advantage. Studies of cell competition in Drosophila have identified an active process of cell assassination and corpse engulfment, and also roles for Myc and the Warts/Hippo tumor suppressor pathway. Here, we discuss the possible relevance of cell competition to cancer.
|Original language||English (US)|
|Number of pages||3|
|State||Published - Jul 15 2008|
ASJC Scopus subject areas
- Cancer Research