Catheter related sepsis during long-term parenteral nutrition in paediatric gastroenterology patients

a study of 185 consecutive central venous catheters

O. Goulet, M. Larchet, J. L. Gaillard, V. Goulet, Dominique M. Jan, Y. Revillon, S. Lortat-Jacob, P. Descamps, C. Ricour

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

We report the results of a prospective study of catheter-related sepsis (CRS) in 154 gastroenterology paediatric patients treated for medical (n = 102) or surgical (n = 52) disorders. Over 2 years, 185 central venous catheters (CVC) were placed, including 155 Broviac and 30 Jonathan Shaw CVC. CVC remained in place 13,331 days (6,539 days of cyclic parenteral nutrition), with a mean catheter life of 72 days. Forty-eight episodes of CRS occurred, most of them due to coagulase-negative staphylococci (n = 29) and Staphylococcus aureus (n = 17). CRS rate was 0.26, with an overall incidence of 1 infection per 278 days of parenteral nutrition (PN). Factors significantly associated with CRS were: age 1-5 years (p < 0.01), a medical indication for treatment (p < 0.001) and summer months of PN (p < 0.01). Interestingly, CRS occurred predominantly (65%) within the first 2 months following CVC placement and the risk of infection correlated with local haemorrhage at the time of insertion (p < 0.01). Appropriate systemic therapy, without removing the catheter, permitted resolution of 90.9% ( 40 44) of all CRS and 100% ( 28 28) of CRS due to coagulase-negative staphylococci.

Original languageEnglish (US)
Pages (from-to)73-78
Number of pages6
JournalClinical Nutrition
Volume9
Issue number2
DOIs
StatePublished - 1990
Externally publishedYes

Fingerprint

Central Venous Catheters
Parenteral Nutrition
Gastroenterology
Sepsis
Catheters
Pediatrics
Coagulase
Staphylococcus
Infection
Staphylococcus aureus
Prospective Studies
Hemorrhage
Incidence
Therapeutics

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Critical Care and Intensive Care Medicine
  • Endocrinology, Diabetes and Metabolism
  • Gastroenterology
  • Health Professions(all)

Cite this

Catheter related sepsis during long-term parenteral nutrition in paediatric gastroenterology patients : a study of 185 consecutive central venous catheters. / Goulet, O.; Larchet, M.; Gaillard, J. L.; Goulet, V.; Jan, Dominique M.; Revillon, Y.; Lortat-Jacob, S.; Descamps, P.; Ricour, C.

In: Clinical Nutrition, Vol. 9, No. 2, 1990, p. 73-78.

Research output: Contribution to journalArticle

Goulet, O. ; Larchet, M. ; Gaillard, J. L. ; Goulet, V. ; Jan, Dominique M. ; Revillon, Y. ; Lortat-Jacob, S. ; Descamps, P. ; Ricour, C. / Catheter related sepsis during long-term parenteral nutrition in paediatric gastroenterology patients : a study of 185 consecutive central venous catheters. In: Clinical Nutrition. 1990 ; Vol. 9, No. 2. pp. 73-78.
@article{98fcf3a82c3a4859a71b800f9fe8af3b,
title = "Catheter related sepsis during long-term parenteral nutrition in paediatric gastroenterology patients: a study of 185 consecutive central venous catheters",
abstract = "We report the results of a prospective study of catheter-related sepsis (CRS) in 154 gastroenterology paediatric patients treated for medical (n = 102) or surgical (n = 52) disorders. Over 2 years, 185 central venous catheters (CVC) were placed, including 155 Broviac and 30 Jonathan Shaw CVC. CVC remained in place 13,331 days (6,539 days of cyclic parenteral nutrition), with a mean catheter life of 72 days. Forty-eight episodes of CRS occurred, most of them due to coagulase-negative staphylococci (n = 29) and Staphylococcus aureus (n = 17). CRS rate was 0.26, with an overall incidence of 1 infection per 278 days of parenteral nutrition (PN). Factors significantly associated with CRS were: age 1-5 years (p < 0.01), a medical indication for treatment (p < 0.001) and summer months of PN (p < 0.01). Interestingly, CRS occurred predominantly (65{\%}) within the first 2 months following CVC placement and the risk of infection correlated with local haemorrhage at the time of insertion (p < 0.01). Appropriate systemic therapy, without removing the catheter, permitted resolution of 90.9{\%} ( 40 44) of all CRS and 100{\%} ( 28 28) of CRS due to coagulase-negative staphylococci.",
author = "O. Goulet and M. Larchet and Gaillard, {J. L.} and V. Goulet and Jan, {Dominique M.} and Y. Revillon and S. Lortat-Jacob and P. Descamps and C. Ricour",
year = "1990",
doi = "10.1016/0261-5614(90)90056-X",
language = "English (US)",
volume = "9",
pages = "73--78",
journal = "Clinical Nutrition",
issn = "0261-5614",
publisher = "Churchill Livingstone",
number = "2",

}

TY - JOUR

T1 - Catheter related sepsis during long-term parenteral nutrition in paediatric gastroenterology patients

T2 - a study of 185 consecutive central venous catheters

AU - Goulet, O.

AU - Larchet, M.

AU - Gaillard, J. L.

AU - Goulet, V.

AU - Jan, Dominique M.

AU - Revillon, Y.

AU - Lortat-Jacob, S.

AU - Descamps, P.

AU - Ricour, C.

PY - 1990

Y1 - 1990

N2 - We report the results of a prospective study of catheter-related sepsis (CRS) in 154 gastroenterology paediatric patients treated for medical (n = 102) or surgical (n = 52) disorders. Over 2 years, 185 central venous catheters (CVC) were placed, including 155 Broviac and 30 Jonathan Shaw CVC. CVC remained in place 13,331 days (6,539 days of cyclic parenteral nutrition), with a mean catheter life of 72 days. Forty-eight episodes of CRS occurred, most of them due to coagulase-negative staphylococci (n = 29) and Staphylococcus aureus (n = 17). CRS rate was 0.26, with an overall incidence of 1 infection per 278 days of parenteral nutrition (PN). Factors significantly associated with CRS were: age 1-5 years (p < 0.01), a medical indication for treatment (p < 0.001) and summer months of PN (p < 0.01). Interestingly, CRS occurred predominantly (65%) within the first 2 months following CVC placement and the risk of infection correlated with local haemorrhage at the time of insertion (p < 0.01). Appropriate systemic therapy, without removing the catheter, permitted resolution of 90.9% ( 40 44) of all CRS and 100% ( 28 28) of CRS due to coagulase-negative staphylococci.

AB - We report the results of a prospective study of catheter-related sepsis (CRS) in 154 gastroenterology paediatric patients treated for medical (n = 102) or surgical (n = 52) disorders. Over 2 years, 185 central venous catheters (CVC) were placed, including 155 Broviac and 30 Jonathan Shaw CVC. CVC remained in place 13,331 days (6,539 days of cyclic parenteral nutrition), with a mean catheter life of 72 days. Forty-eight episodes of CRS occurred, most of them due to coagulase-negative staphylococci (n = 29) and Staphylococcus aureus (n = 17). CRS rate was 0.26, with an overall incidence of 1 infection per 278 days of parenteral nutrition (PN). Factors significantly associated with CRS were: age 1-5 years (p < 0.01), a medical indication for treatment (p < 0.001) and summer months of PN (p < 0.01). Interestingly, CRS occurred predominantly (65%) within the first 2 months following CVC placement and the risk of infection correlated with local haemorrhage at the time of insertion (p < 0.01). Appropriate systemic therapy, without removing the catheter, permitted resolution of 90.9% ( 40 44) of all CRS and 100% ( 28 28) of CRS due to coagulase-negative staphylococci.

UR - http://www.scopus.com/inward/record.url?scp=0025215742&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025215742&partnerID=8YFLogxK

U2 - 10.1016/0261-5614(90)90056-X

DO - 10.1016/0261-5614(90)90056-X

M3 - Article

VL - 9

SP - 73

EP - 78

JO - Clinical Nutrition

JF - Clinical Nutrition

SN - 0261-5614

IS - 2

ER -