Catheter ablation for ventricular tachyarrhythmias in patients supported by continuous-flow left ventricular assist devices

Arthur R. Garan, Vivek Iyer, William Whang, Kanika P. Mody, Melana Yuzefpolskaya, Paolo C. Colombo, Rosie Te-Frey, Hiroo Takayama, Yoshifumi Naka, Hasan Garan, Ulrich P. Jorde, Nir Uriel

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

Ventricular arrhythmias (VAs) are common after implantation of a left ventricular assist device (LVAD) and in a subset of patients may be refractory to medication. Morbidity from VA in this population includes right ventricular failure (RVF). We sought to evaluate the efficacy of catheter ablation for VA in patients with LVAD. A retrospective analysis of patients supported by continuous-flow LVAD referred for catheter ablation of ventricular tachycardia (VT) between 2008 and the present was performed. Seven patients were referred for VT ablation an average of 236 ± 292 days after LVAD implantation. Three patients (42.9%) developed RVF in the setting of intractable arrhythmias. A transfemoral approach was used for six patients (85.7%) and an epicardial for one patient (14.3%). The clinical VT was inducible and successfully ablated in six patients (85.7%). The location of these arrhythmias was apical in three cases (42.9%). A total of 13 VTs were ablated in seven patients. Although the majority had reduction in VA frequency, recurrent VAs were observed in six patients (85.7%). One patient (14.3%) experienced a bleeding complication after the procedure. For patients with a high VA burden after LVAD implantation, VT ablation is safe and feasible, but VA frequently recurs.

Original languageEnglish (US)
Pages (from-to)311-316
Number of pages6
JournalASAIO Journal
Volume60
Issue number3
DOIs
StatePublished - Jan 1 2014
Externally publishedYes

Keywords

  • Left ventricular assist device
  • ablation
  • ventricular tachycardia

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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  • Cite this

    Garan, A. R., Iyer, V., Whang, W., Mody, K. P., Yuzefpolskaya, M., Colombo, P. C., Te-Frey, R., Takayama, H., Naka, Y., Garan, H., Jorde, U. P., & Uriel, N. (2014). Catheter ablation for ventricular tachyarrhythmias in patients supported by continuous-flow left ventricular assist devices. ASAIO Journal, 60(3), 311-316. https://doi.org/10.1097/MAT.0000000000000061