@article{b63b00e2ccf9490a8485afba2f1bc6a8,
title = "Carcinoma of the uterine cervix metastatic to behind the zygomatic arch: A case report",
abstract = "Purpose: We propose to present a novel case of a genital malignancy metastatic to the head and neck. Carcinoma of the uterine cervix is the third most frequent malignancy of the female genital tract. Early detection and improved radiation and surgical techniques have resulted in better control of the pelvic tumor and a greater incidence of distant metastasis. Metastases to the soft tissue of the head and neck region have not been reported. Methods: We present the first known case of a 35-year-old woman with cancer of the uterine cervix who presented with metastasis to the soft tissue behind the zygomatic arch. Results: The patient received radiation therapy to the zygomatic region and cisplatin therapy with a near-complete remission. Conclusion: This case shows that not all squamous cell cancers detected above the clavicles are from a thoracic or a head and neck primary tumor. The atypical location should alert the physician to suspect distant metastasis, rather than locoregional disease.",
author = "Challagalla, {Jagathi D.} and Richard Smith and Robin Mitnick and Dwayne Breining and Scott Wadler",
note = "Funding Information: Carcinoma of the cervix is the third most frequent cancer of the female genital tract.r It is the seventh most common cancer in women in the United States and the most common cancer in women in some developing countries2 Early detection and improved radiation and surgical techniques used within the past four decades in the management of this malignancy have resulted in better control of the pelvic tumor and longer survival3 These improved results have been accompanied by a greater incidence of distant metastases.3-5 Spread by hematogenous dissemination is rela- From the Departments of Oncology, Otorhinolaryngology, Neuroradiology, and Cytopathology, Montefiore Medical Center, Bronx, NY. Supported in part by Cancer Center Support Grants CA 13330 and 63422 from the National Cancer Institute, Bethesda, MD. Address reprint requests to Scott Wadler, MD, Department of Oncology, Hofheimer 100, Montefiore Medical Center, 111 E 210th St, Bronx, NY 10467. Copyright 0 1999 by W.B. Saunders Company 0196-0709/99/2003-0013$10.00/0 tively unusual, but the risk increases with more advanced stages .4,6 The lo-year actuarial incidence of distant metastases in patients treated with radiation alone was 3% in stage IA, 16% in stage IB, 26% in stage IIA, 31% in stage IIB, 39% in stage III, and 75% in stage IVA.3 The most commonly involved sites are lung, bone, liver, and extrapelvic lymph nodes.7,8 We present the first known patient with cervical cancer who presented with metastasis to the soft tissue of the left zygomatic region.",
year = "1999",
doi = "10.1016/S0196-0709(99)90072-8",
language = "English (US)",
volume = "20",
pages = "195--197",
journal = "American Journal of Otolaryngology - Head and Neck Medicine and Surgery",
issn = "0196-0709",
publisher = "W.B. Saunders Ltd",
number = "3",
}