Carbamazepine-induced constipation

Alan B. Ettinger, Shlomo Shinnar, Mark J. Sinnett, Solomon L. Moshe

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We report three patients who developed constipation as an adverse effect of carbamazepine (CBZ) therapy. Constipation occurred within a few days of CBZ introduction, resolved after CBZ discontinuation, and was not dose-responsive. It was refractory to the concomitant use of oral laxatives in two cases, necessitating CBZ discontinuation. In a third patient, constipation was controlled by a fiber agent, allowing continuation of CBZ therapy. Potential mechanisms for this idiosyncratic, poorly reported adverse event are discussed.

Original languageEnglish (US)
Pages (from-to)191-193
Number of pages3
JournalJournal of Epilepsy
Volume5
Issue number3
DOIs
StatePublished - 1992

Fingerprint

Carbamazepine
Constipation
Laxatives
Therapeutics

Keywords

  • Carbamazepine
  • Constipation
  • Gastrointestinal disorder

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Carbamazepine-induced constipation. / Ettinger, Alan B.; Shinnar, Shlomo; Sinnett, Mark J.; Moshe, Solomon L.

In: Journal of Epilepsy, Vol. 5, No. 3, 1992, p. 191-193.

Research output: Contribution to journalArticle

Ettinger, Alan B. ; Shinnar, Shlomo ; Sinnett, Mark J. ; Moshe, Solomon L. / Carbamazepine-induced constipation. In: Journal of Epilepsy. 1992 ; Vol. 5, No. 3. pp. 191-193.
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