Cannabinoid Hyperemesis Syndrome: A Case Series and Review of Previous Reports

Stephen E. Nicolson, Lex Denysenko, J. Loretta Mulcare, Jose P. Vito, Brenda Chabon

Research output: Contribution to journalArticle

Abstract

Background: Cannabis is the most commonly used illicit substance worldwide. Cannabinoids or cannabinoid receptor agonists are often used to treat nausea, vomiting, and anorexia. However, in recent years, several medical journals have published reports of patients with nausea and vomiting thought to be induced by chronic cannabis use. Objective: The authors seek to inform readers about Cannabinoid Hyperemesis Syndrome (CHS). Method: The authors describe four patients with chronic cannabis abuse, episodic, intractable nausea and vomiting, and compulsive hot water bathing. Previous cases of CHS are reviewed, pathophysiology is hypothesized, and difficulties with making the diagnosis are discussed. Conclusion: CHS should be strongly considered in the differential diagnosis of patients with intractable vomiting and/or compulsive hot water bathing.

Original languageEnglish (US)
JournalPsychosomatics
DOIs
Publication statusAccepted/In press - 2012

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ASJC Scopus subject areas

  • Applied Psychology
  • Psychiatry and Mental health
  • Arts and Humanities (miscellaneous)

Cite this

Nicolson, S. E., Denysenko, L., Mulcare, J. L., Vito, J. P., & Chabon, B. (Accepted/In press). Cannabinoid Hyperemesis Syndrome: A Case Series and Review of Previous Reports. Psychosomatics. https://doi.org/10.1016/j.psym.2012.01.003