Canine colonic anastomoses reinforced with dye-enhanced fibrinogen and a diode laser

Steven K. Libutti, Mehmet C. Oz, Kenneth A. Forde, Joseph S. Auteri, Jeffrey P. Johnson, Lawrence S. Bass, Michael R. Treat

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Leakage from colonic anastomoses is a common cause of morbidity in patients recovering from bowel surgery. We evaluated a technique of laser-fibrinogen reinforcement to strengthen colonic anastomoses in a canine model. After creation of eight single-layer interrupted suture anastomoses in six dogs, indocyanine green-dye-enhanced fibrinogen was topically applied to the serosal surface and exposed to 808 mm diode laser energy. Immediately following colonic anastomosis, the mean leakage pressure was 137±22 mm Hg in the group (n=8) using sutures alone and 326±67 mm Hg (P<0.001) in the group (n=8) after the sutured anastomosis was reinforced with lasered-fibrinogen. On histological examination, no evidence of thermal injury to the tissue edges was noted and a layer of fibrinogen bridged the anastomotic gap. Laser dye-enhanced fibrinogen reinforcement significantly enhances the strength of sutured colonic anastomoses without causing appreciable thermal injury to the host tissues.

Original languageEnglish (US)
Pages (from-to)97-99
Number of pages3
JournalSurgical Endoscopy
Volume4
Issue number2
DOIs
StatePublished - Jun 1990
Externally publishedYes

Fingerprint

Semiconductor Lasers
Fibrinogen
Canidae
Coloring Agents
Sutures
Hot Temperature
Dye Lasers
Indocyanine Green
Wounds and Injuries
Lasers
Dogs
Morbidity
Pressure

Keywords

  • 808 nm diode lasers
  • Colonic anastomosis
  • Fibrinogen
  • Indocyanine green dye
  • Laser welding

ASJC Scopus subject areas

  • Surgery

Cite this

Libutti, S. K., Oz, M. C., Forde, K. A., Auteri, J. S., Johnson, J. P., Bass, L. S., & Treat, M. R. (1990). Canine colonic anastomoses reinforced with dye-enhanced fibrinogen and a diode laser. Surgical Endoscopy, 4(2), 97-99. https://doi.org/10.1007/BF00591269

Canine colonic anastomoses reinforced with dye-enhanced fibrinogen and a diode laser. / Libutti, Steven K.; Oz, Mehmet C.; Forde, Kenneth A.; Auteri, Joseph S.; Johnson, Jeffrey P.; Bass, Lawrence S.; Treat, Michael R.

In: Surgical Endoscopy, Vol. 4, No. 2, 06.1990, p. 97-99.

Research output: Contribution to journalArticle

Libutti, SK, Oz, MC, Forde, KA, Auteri, JS, Johnson, JP, Bass, LS & Treat, MR 1990, 'Canine colonic anastomoses reinforced with dye-enhanced fibrinogen and a diode laser', Surgical Endoscopy, vol. 4, no. 2, pp. 97-99. https://doi.org/10.1007/BF00591269
Libutti SK, Oz MC, Forde KA, Auteri JS, Johnson JP, Bass LS et al. Canine colonic anastomoses reinforced with dye-enhanced fibrinogen and a diode laser. Surgical Endoscopy. 1990 Jun;4(2):97-99. https://doi.org/10.1007/BF00591269
Libutti, Steven K. ; Oz, Mehmet C. ; Forde, Kenneth A. ; Auteri, Joseph S. ; Johnson, Jeffrey P. ; Bass, Lawrence S. ; Treat, Michael R. / Canine colonic anastomoses reinforced with dye-enhanced fibrinogen and a diode laser. In: Surgical Endoscopy. 1990 ; Vol. 4, No. 2. pp. 97-99.
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