Can intensive care unit delirium be prevented and reduced? lessons learned and future directions

S. Jean Hsieh, E. Wesley Ely, Michelle Ng Gong

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Delirium is a form of acute brain injury that occurs in up to 80% of critically ill patients. It is a source of enormous societal and financial burdens due to increased mortality, prolonged intensive care unit (ICU) and hospital stays, and long-term neuropsychological and functional deficits in ICU survivors. These poor outcomes are not only independently associated with the development of delirium but are also associated with increasing delirium duration. Therefore, interventions should strive both to prevent the occurrence of ICU delirium and to limit its persistence. Both patient-centered and ICU-Acquired risk factors need to be addressed early in the ICU course to maximize the efficacy of prevention strategies and to improve long-term outcomes of ICU patients. In this article, we review strategies for early detection of patientswho are delirious andwho are at high risk for developing delirium, and we present a clinically useful ICU delirium prevention and reduction strategy for clinicians to incorporate into their daily practice.

Original languageEnglish (US)
Pages (from-to)648-656
Number of pages9
JournalAnnals of the American Thoracic Society
Volume10
Issue number6
DOIs
StatePublished - Dec 2013

Fingerprint

Delirium
Intensive Care Units
Patient-Centered Care
Direction compound
Critical Illness
Brain Injuries
Survivors
Length of Stay
Mortality

Keywords

  • Critical illness
  • Delirium
  • Early therapy
  • Prevention
  • Risk factors

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Can intensive care unit delirium be prevented and reduced? lessons learned and future directions. / Hsieh, S. Jean; Ely, E. Wesley; Gong, Michelle Ng.

In: Annals of the American Thoracic Society, Vol. 10, No. 6, 12.2013, p. 648-656.

Research output: Contribution to journalArticle

@article{571bdd558fcd41b68860dac1c34dd7bd,
title = "Can intensive care unit delirium be prevented and reduced? lessons learned and future directions",
abstract = "Delirium is a form of acute brain injury that occurs in up to 80{\%} of critically ill patients. It is a source of enormous societal and financial burdens due to increased mortality, prolonged intensive care unit (ICU) and hospital stays, and long-term neuropsychological and functional deficits in ICU survivors. These poor outcomes are not only independently associated with the development of delirium but are also associated with increasing delirium duration. Therefore, interventions should strive both to prevent the occurrence of ICU delirium and to limit its persistence. Both patient-centered and ICU-Acquired risk factors need to be addressed early in the ICU course to maximize the efficacy of prevention strategies and to improve long-term outcomes of ICU patients. In this article, we review strategies for early detection of patientswho are delirious andwho are at high risk for developing delirium, and we present a clinically useful ICU delirium prevention and reduction strategy for clinicians to incorporate into their daily practice.",
keywords = "Critical illness, Delirium, Early therapy, Prevention, Risk factors",
author = "Hsieh, {S. Jean} and Ely, {E. Wesley} and Gong, {Michelle Ng}",
year = "2013",
month = "12",
doi = "10.1513/AnnalsATS.201307-232FR",
language = "English (US)",
volume = "10",
pages = "648--656",
journal = "Annals of the American Thoracic Society",
issn = "2325-6621",
publisher = "American Thoracic Society",
number = "6",

}

TY - JOUR

T1 - Can intensive care unit delirium be prevented and reduced? lessons learned and future directions

AU - Hsieh, S. Jean

AU - Ely, E. Wesley

AU - Gong, Michelle Ng

PY - 2013/12

Y1 - 2013/12

N2 - Delirium is a form of acute brain injury that occurs in up to 80% of critically ill patients. It is a source of enormous societal and financial burdens due to increased mortality, prolonged intensive care unit (ICU) and hospital stays, and long-term neuropsychological and functional deficits in ICU survivors. These poor outcomes are not only independently associated with the development of delirium but are also associated with increasing delirium duration. Therefore, interventions should strive both to prevent the occurrence of ICU delirium and to limit its persistence. Both patient-centered and ICU-Acquired risk factors need to be addressed early in the ICU course to maximize the efficacy of prevention strategies and to improve long-term outcomes of ICU patients. In this article, we review strategies for early detection of patientswho are delirious andwho are at high risk for developing delirium, and we present a clinically useful ICU delirium prevention and reduction strategy for clinicians to incorporate into their daily practice.

AB - Delirium is a form of acute brain injury that occurs in up to 80% of critically ill patients. It is a source of enormous societal and financial burdens due to increased mortality, prolonged intensive care unit (ICU) and hospital stays, and long-term neuropsychological and functional deficits in ICU survivors. These poor outcomes are not only independently associated with the development of delirium but are also associated with increasing delirium duration. Therefore, interventions should strive both to prevent the occurrence of ICU delirium and to limit its persistence. Both patient-centered and ICU-Acquired risk factors need to be addressed early in the ICU course to maximize the efficacy of prevention strategies and to improve long-term outcomes of ICU patients. In this article, we review strategies for early detection of patientswho are delirious andwho are at high risk for developing delirium, and we present a clinically useful ICU delirium prevention and reduction strategy for clinicians to incorporate into their daily practice.

KW - Critical illness

KW - Delirium

KW - Early therapy

KW - Prevention

KW - Risk factors

UR - http://www.scopus.com/inward/record.url?scp=84892143295&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84892143295&partnerID=8YFLogxK

U2 - 10.1513/AnnalsATS.201307-232FR

DO - 10.1513/AnnalsATS.201307-232FR

M3 - Article

VL - 10

SP - 648

EP - 656

JO - Annals of the American Thoracic Society

JF - Annals of the American Thoracic Society

SN - 2325-6621

IS - 6

ER -