Caenorhabditis elegans unc-37/groucho interacts genetically with components of the transcriptional mediator complex

Hong Zhang, Scott W. Emmons

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Groucho functions as a general corepressor by modulating chromatin structure and has a widespread role in many developmental processes. Here we show that Groucho may also interact with the basal transcriptional machinery. Mutations in Caenorhabditis elegans groucho interact with mutations in components of the transcriptional Mediator complex, resulting in synthetic lethality and loss of male sensory neurons.

Original languageEnglish (US)
Pages (from-to)799-803
Number of pages5
JournalGenetics
Volume160
Issue number2
StatePublished - 2002

Fingerprint

Mediator Complex
Caenorhabditis elegans
Co-Repressor Proteins
Mutation
Sensory Receptor Cells
Chromatin

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

Cite this

Caenorhabditis elegans unc-37/groucho interacts genetically with components of the transcriptional mediator complex. / Zhang, Hong; Emmons, Scott W.

In: Genetics, Vol. 160, No. 2, 2002, p. 799-803.

Research output: Contribution to journalArticle

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