Breast conservation for male breast cancer

Case report of intraoperative radiation

Ameer Gomberawalla, Peter Liou, Rebecca Martinez, Raj Rajpara, Eileen Connolly, David Horowitz, Sheldon M. Feldman

Research output: Contribution to journalArticle

Abstract

Male breast cancer (MBC) comprises <1% of all breast cancers in the United States. MBC is typically treated with total mastectomy while the majority of female breast cancer is treated with breast conservation therapy combined with various forms of radiation. One method that has developed over the last two decades is the use of intraoperative radiation therapy (IORT) as a type of accelerated partial breast irradiation to direct the treatment field to the tumor bed. Since overall prognosis and systemic therapy recommendations for MBC are similar to breast cancer in women, we describe the first case of MBC treated with BCS and IORT. Our patient is a 62-year-old male who was found to have a right breast 1.6 cm palpable mass at the 10:00 position 1 cm radially from the nipple. Core biopsy demonstrated invasive ductal carcinoma, moderately differentiated, estrogen and progesterone receptor positive, and Her 2 Negative. The patient had a strong desire for breast conservation, and needed to minimize daily radiation treatments due to his work schedule. After discussion among our multidisciplinary tumor board, we felt this patient to be suitable for BCS and IORT given his age, favorable tumor subtype, size, and clinically early stage breast cancer. A right axillary sentinel lymph node biopsy and central lumpectomy was performed. The INTRABEAM device (Carl Zeiss Meditec, Oberkochen, Germany) was utilized for radiation delivery. The patient had negative margins on his final pathology. The postoperative course was uneventful and at the 6 month follow-up visit there were no issues and he had an excellent cosmetic outcome. BCS and IORT is an option in appropriately selected male patients with favorable subtype early stage breast cancer.

Original languageEnglish (US)
Pages (from-to)74-77
Number of pages4
JournalBreast Journal
Volume24
Issue number1
DOIs
StatePublished - Jan 1 2018

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Male Breast Neoplasms
Breast
Radiation
Breast Neoplasms
Radiotherapy
Segmental Mastectomy
Simple Mastectomy
Sentinel Lymph Node Biopsy
Neoplasms
Ductal Carcinoma
Nipples
Progesterone Receptors
Cosmetics
Estrogen Receptors
Germany
Appointments and Schedules
Therapeutics
Pathology
Biopsy
Equipment and Supplies

Keywords

  • breast cancer
  • breast conservation surgery
  • intraoperative radiation
  • male breast cancer

ASJC Scopus subject areas

  • Internal Medicine
  • Surgery
  • Oncology

Cite this

Gomberawalla, A., Liou, P., Martinez, R., Rajpara, R., Connolly, E., Horowitz, D., & Feldman, S. M. (2018). Breast conservation for male breast cancer: Case report of intraoperative radiation. Breast Journal, 24(1), 74-77. https://doi.org/10.1111/tbj.12847

Breast conservation for male breast cancer : Case report of intraoperative radiation. / Gomberawalla, Ameer; Liou, Peter; Martinez, Rebecca; Rajpara, Raj; Connolly, Eileen; Horowitz, David; Feldman, Sheldon M.

In: Breast Journal, Vol. 24, No. 1, 01.01.2018, p. 74-77.

Research output: Contribution to journalArticle

Gomberawalla, A, Liou, P, Martinez, R, Rajpara, R, Connolly, E, Horowitz, D & Feldman, SM 2018, 'Breast conservation for male breast cancer: Case report of intraoperative radiation', Breast Journal, vol. 24, no. 1, pp. 74-77. https://doi.org/10.1111/tbj.12847
Gomberawalla A, Liou P, Martinez R, Rajpara R, Connolly E, Horowitz D et al. Breast conservation for male breast cancer: Case report of intraoperative radiation. Breast Journal. 2018 Jan 1;24(1):74-77. https://doi.org/10.1111/tbj.12847
Gomberawalla, Ameer ; Liou, Peter ; Martinez, Rebecca ; Rajpara, Raj ; Connolly, Eileen ; Horowitz, David ; Feldman, Sheldon M. / Breast conservation for male breast cancer : Case report of intraoperative radiation. In: Breast Journal. 2018 ; Vol. 24, No. 1. pp. 74-77.
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