BRCA1, TP53, and CHEK2 germline mutations in uterine serous carcinoma

Medicine & Life Sciences

• Checkpoint Kinase 2 100%
• BRCA1 Protein 89%
• Germ-Line Mutation 67%
• Carcinoma 39%
• Mutation 23%
• Neoplasms 19%
• Breast Neoplasms 19%
• Hereditary Nonpolyposis Colorectal Neoplasms 15%
• DNA Mismatch Repair 14%
• Mutation Rate 12%
• Tumor Suppressor Genes 11%
• Histology 9%
• MutL Protein Homolog 1 9%
• Li-Fraumeni Syndrome 9%
• Hereditary Neoplastic Syndromes 9%
• Proteins 8%
• Fanconi Anemia 8%
• Genes 7%
• Loss of Function Mutation 6%
• Genetic Testing 6%
• High-Throughput Nucleotide Sequencing 5%
• History 4%
• Population 2%