Boron nitride nanotubes are noncytotoxic and can be functionalized for interaction with proteins and cells

Xing Chen, Peng Wu, Michael Rousseas, David Okawa, Zev Gartner, Alex Zettl, Carolyn R. Bertozzi

Research output: Contribution to journalArticle

324 Citations (Scopus)

Abstract

We report the discovery that boron nitride nanotubes (BNNTs), isosteres of CNTs with unique physical properties, are inherently noncytotoxic. Furthermore, we developed a biomemetic coating strategy to interface BNNTs with proteins and cells. Finally, we showed that BNNTs can deliver DNA oligomers to the interior of cells with no apparent toxicity. This work suggests that BNNTs may be superior to CNTs for use as biological probes and in biomaterials.

Original languageEnglish (US)
Pages (from-to)890-891
Number of pages2
JournalJournal of the American Chemical Society
Volume131
Issue number3
DOIs
StatePublished - Jan 28 2009
Externally publishedYes

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Nanotubes
Boron nitride
Proteins
Biocompatible Materials
Oligomers
Biomaterials
Toxicity
DNA
Physical properties
Coatings
boron nitride

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this

Boron nitride nanotubes are noncytotoxic and can be functionalized for interaction with proteins and cells. / Chen, Xing; Wu, Peng; Rousseas, Michael; Okawa, David; Gartner, Zev; Zettl, Alex; Bertozzi, Carolyn R.

In: Journal of the American Chemical Society, Vol. 131, No. 3, 28.01.2009, p. 890-891.

Research output: Contribution to journalArticle

Chen, Xing ; Wu, Peng ; Rousseas, Michael ; Okawa, David ; Gartner, Zev ; Zettl, Alex ; Bertozzi, Carolyn R. / Boron nitride nanotubes are noncytotoxic and can be functionalized for interaction with proteins and cells. In: Journal of the American Chemical Society. 2009 ; Vol. 131, No. 3. pp. 890-891.
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