@article{93d51b3bb32e42b7a1dd07ebd346c6f9,
title = "Bone marrow cell therapy ameliorates and reverses chagasic cardiomyopathy in a mouse model",
abstract = "Chronic chagasic cardiomyopathy, which is caused by the protozoan Trypanosoma cruzi, is a major cause of heart failure in Latin America. It is a disease for which effective treatment in its advanced clinical forms is lacking. We have previously shown that bone marrow mononuclear cell (BMC) transplantation is effective in reducing inflammation and fibrosis in the mouse model of Chagas disease. The present study used magnetic resonance imaging to assess changes in the cardiac morphology of infected mice after therapy with BMCs. Serial imaging of the BMC-treated mice revealed regression of the right ventricular dilatation typically observed in the chagasic mouse model.",
author = "Goldenberg, {Regina C.S.} and Jelicks, {Linda A.} and Fortes, {Fabio S.A.} and Weiss, {Louis M.} and Rocha, {Leonardo L.} and Dazhi Zhao and {De Carvalho}, {Antonio Campos} and Spray, {David C.} and Tanowitz, {Herbert B.}",
note = "Funding Information: Received 24 August 2007; accepted 7 September 2007; electronically published 29 January 2008. Potential conflicts of interest: none reported. Financial support: National Institutes of Health (grant R01-HL073732); Fogarty International Training Grant (grant D43TW007129). a R.C.S.G. and L.A.J. contributed equally to this work. Reprints or correspondence: Dr. Linda A. Jelicks, MRRC 301, Dept. of Physiology and Biophysics, Albert Einstein College of Medicine, 1300 Morris Park Ave., Bronx, NY 10461 (Jelicks@aecom.yu.edu).",
year = "2008",
month = feb,
day = "15",
doi = "10.1086/526793",
language = "English (US)",
volume = "197",
pages = "544--547",
journal = "Journal of Infectious Diseases",
issn = "0022-1899",
publisher = "Oxford University Press",
number = "4",
}