Abstract
Fungal urinary tract infection has become a frequent clinical entity, Despite limited evaluation of its efficacy, bladder irrigation with amphotericin B has become the usual means of therapy for such infections. The outcome of treatment with amphotericin B bladder irrigation for an average of 5 days for 95 hospitalized patientswith funguria (mean age, 75 years) during a 14-month period is presented. All patients who received treatment were identified from pharmacy records; those for whom urine culture results were obtained after treatment were studied. Fever and/or pyuria was identified in the majority of cases. Funguria was eradicated in 80% (confidence interval, 72%-88%). Concomitant diabetes mellitus or the previous use of indwelling bladder catheters did not alter response to treatment. The mortality rate following treatment of funguria was 39%, compared to 30.5% for a similarpopulation during the same period. Amphotericin B bladder irrigation may not prove to be idealtherapy despite the fact that it initially eradicated funguria in the majority of subjects in this study.
Original language | English (US) |
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Pages (from-to) | 313-318 |
Number of pages | 6 |
Journal | Clinical Infectious Diseases |
Volume | 18 |
Issue number | 3 |
DOIs | |
State | Published - Mar 1994 |
ASJC Scopus subject areas
- Microbiology (medical)
- Infectious Diseases