Bioavailability of nickel in single-wall carbon nanotubes

Xinyuan Liu, Volkan Gurel, Daniel Morris, David W. Murray, Anatoly Zhitkovich, Agnes B. Kane, Robert H. Hurt

Research output: Contribution to journalArticle

142 Citations (Scopus)

Abstract

A study was conducted to perform measurements of nickel (Ni) bioavailability in carbon nanotubes (CNT). It was demonstrated that despite encapsulation, toxicologically significant quantities of nickel are released from a range of single-wall carbon nanotube samples and transported across the plasma membrane into human lung epithelial cells. It was also found that the Ni release varied significantly as a function of nanotube source and processing methods. It was observed that cellular bioavailability of Ni caused a major problem for the carcinogenecity of nickel. It was also found that the ability of various nickel compounds to be taken up directly by cells influenced intracellular nickel levels and their carcinogenic activity was proportional to cellular uptake.

Original languageEnglish (US)
Pages (from-to)2790-2796
Number of pages7
JournalAdvanced Materials
Volume19
Issue number19
DOIs
StatePublished - Oct 5 2007
Externally publishedYes

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Carbon Nanotubes
Nickel
Carbon nanotubes
Nickel compounds
Cell membranes
Encapsulation
Nanotubes
Biological Availability
Processing

ASJC Scopus subject areas

  • Materials Science(all)

Cite this

Liu, X., Gurel, V., Morris, D., Murray, D. W., Zhitkovich, A., Kane, A. B., & Hurt, R. H. (2007). Bioavailability of nickel in single-wall carbon nanotubes. Advanced Materials, 19(19), 2790-2796. https://doi.org/10.1002/adma.200602696

Bioavailability of nickel in single-wall carbon nanotubes. / Liu, Xinyuan; Gurel, Volkan; Morris, Daniel; Murray, David W.; Zhitkovich, Anatoly; Kane, Agnes B.; Hurt, Robert H.

In: Advanced Materials, Vol. 19, No. 19, 05.10.2007, p. 2790-2796.

Research output: Contribution to journalArticle

Liu, X, Gurel, V, Morris, D, Murray, DW, Zhitkovich, A, Kane, AB & Hurt, RH 2007, 'Bioavailability of nickel in single-wall carbon nanotubes', Advanced Materials, vol. 19, no. 19, pp. 2790-2796. https://doi.org/10.1002/adma.200602696
Liu X, Gurel V, Morris D, Murray DW, Zhitkovich A, Kane AB et al. Bioavailability of nickel in single-wall carbon nanotubes. Advanced Materials. 2007 Oct 5;19(19):2790-2796. https://doi.org/10.1002/adma.200602696
Liu, Xinyuan ; Gurel, Volkan ; Morris, Daniel ; Murray, David W. ; Zhitkovich, Anatoly ; Kane, Agnes B. ; Hurt, Robert H. / Bioavailability of nickel in single-wall carbon nanotubes. In: Advanced Materials. 2007 ; Vol. 19, No. 19. pp. 2790-2796.
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