Bioaccumulation as a mechanism of microbiome/drug interactions

Ziv Cohen; Libusha Kelly

doi:10.1016/j.tim.2021.12.003

Bioaccumulation as a mechanism of microbiome/drug interactions

Ziv Cohen, Libusha Kelly

Systems & Computational Biology

Research output: Contribution to journal › Short survey › peer-review

2 Scopus citations

Abstract

Microbes of the human gut can change drug disposition in the human body and gut ecology via 'bioaccumulation', a process in which bacteria take up compounds intracellularly without chemically modifying them or experiencing changes in growth, as described in Klünemann et al. This work expands current understanding of the types of drug–bacterial interactions in the gut environment.

Original language	English (US)
Pages (from-to)	99-101
Number of pages	3
Journal	Trends in Microbiology
Volume	30
Issue number	2
DOIs	https://doi.org/10.1016/j.tim.2021.12.003
State	Published - Feb 2022

ASJC Scopus subject areas

Microbiology
Microbiology (medical)
Virology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.tim.2021.12.003

Cite this

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title = "Bioaccumulation as a mechanism of microbiome/drug interactions",

abstract = "Microbes of the human gut can change drug disposition in the human body and gut ecology via 'bioaccumulation', a process in which bacteria take up compounds intracellularly without chemically modifying them or experiencing changes in growth, as described in Kl{\"u}nemann et al. This work expands current understanding of the types of drug–bacterial interactions in the gut environment.",

author = "Ziv Cohen and Libusha Kelly",

note = "Publisher Copyright: {\textcopyright} 2021 Elsevier Ltd",

year = "2022",

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doi = "10.1016/j.tim.2021.12.003",

language = "English (US)",

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AU - Kelly, Libusha

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AB - Microbes of the human gut can change drug disposition in the human body and gut ecology via 'bioaccumulation', a process in which bacteria take up compounds intracellularly without chemically modifying them or experiencing changes in growth, as described in Klünemann et al. This work expands current understanding of the types of drug–bacterial interactions in the gut environment.

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DO - 10.1016/j.tim.2021.12.003

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C2 - 34952771

AN - SCOPUS:85121669996

SN - 0966-842X

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JO - Trends in Microbiology

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ER -

Bioaccumulation as a mechanism of microbiome/drug interactions

Abstract

ASJC Scopus subject areas

UN SDGs

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