Endodermal sinus tumor, also called yolk sac tumor, is a kind of nonseminomatous germ cell tumor. It is thought to be derived from differentiation of malignant germ cells along the extraembryonic yolk sac lineage. Extragonadal nonseminomatous germ cell tumor should be considered in the differential diagnosis of histologically poorly differentiated cancer and of neoplasms of an unknown primary site in young men with midline disease. We report a case of endodermal sinus tumor manifesting as rapidly growing bilateral lung masses in a 48-year-old woman.
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