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Patients:One 20-year-old female inpatient.

TypeofStudy:A case report describing the successful treatment with Famvir of a patient with disseminated herpes simplex virus type II infection and herpes hepatitis.

DosageDuration:Dosage and duration not stated.

Results:The patient showed rapid clinical improvement after Famvir administration. Liver enzyme levels concurrently reduced to normal range.

Indications:1 patient with disseminated herpes simplex type II infection on the face and on the external genitalia, and herpes hepatitis.

AdverseEffects:No adverse events were mentioned.

AuthorsConclusions:Our patient was given a standard regimen of famciclovir. She subsequently showed rapid clinical improvement, and her liver enzymes concurrently decreased, falling within normal range.

FreeText:The patient presented with a 1-week history of nausea, vomiting, fever, diffuse abdominal pain, brown vaginal discharge, and dysuria. 2 days after the onset of symptoms, she noticed 2 vesicles on her face and on the following week, similar lesions were also observed on her external genitalia. The patient had an elevated temperature at 38.6°C (100.4°F), tachycardia (120 beats/minute), right upper quadrant tenderness but without peritoneal signs. Laboratory findings revealed normocytic anemia and elevated liver enzyme levels (alkaline phosphatase 77 IU/L, alanine transaminase 129 IU/L, aspartate transaminase 110 IU/L and lactate dehydrogenase 416 IU/L). Punch biopsy of a vesicular lesion on the thigh was consistent with herpetic blister. Direct antigen detection and herpes simplex virus isolation from a direct smear were positive for herpes simplex virus type II, leading to a diagnosis of disseminated herpes simplex virus type II infection and herpes hepatitis. The patient was initiated with a standard therapy of Famvir.