TY - JOUR
T1 - Babesiosis in asplenic hosts
AU - Rowin, Kenneth S.
AU - Tanowitz, Herbert B.
AU - Rubinstein, Arye
AU - Kunkel, Mark
AU - Wittner, Murray
N1 - Funding Information:
Acknowledgements We would like to thank Dr. Liya Levinskaya for translating a Russian language paper and Dr. George Healy for his thoughtful comments and suggestions. Grant Support: Grants l-T-32-AI-07183 and AI-12770, National Institutes of Health.
PY - 1984
Y1 - 1984
N2 - A case of babesiosis in an asplenic individual is reported. A course characterized by fever, haemolysis, hepatitis, depressed mental status and non-cardiac pulmonary oedema was observed. Studies performed on the patient's lymphocytes revealed profound depression in mitogenic responses during her acute disease which returned to normal with recovery. Serum factor(s) were implicated in causing these changes. Review of the literature on babesiosis in asplenic hosts revealed European patients with disease caused by bovine species of Babesia are at significantly higher risk of a fatal outcome than North Americans with disease caused by murine species.
AB - A case of babesiosis in an asplenic individual is reported. A course characterized by fever, haemolysis, hepatitis, depressed mental status and non-cardiac pulmonary oedema was observed. Studies performed on the patient's lymphocytes revealed profound depression in mitogenic responses during her acute disease which returned to normal with recovery. Serum factor(s) were implicated in causing these changes. Review of the literature on babesiosis in asplenic hosts revealed European patients with disease caused by bovine species of Babesia are at significantly higher risk of a fatal outcome than North Americans with disease caused by murine species.
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U2 - 10.1016/0035-9203(84)90054-3
DO - 10.1016/0035-9203(84)90054-3
M3 - Article
C2 - 6333094
AN - SCOPUS:0021195435
SN - 0035-9203
VL - 78
SP - 442
EP - 444
JO - Transactions of the Royal Society of Tropical Medicine and Hygiene
JF - Transactions of the Royal Society of Tropical Medicine and Hygiene
IS - 4
ER -