B-raf and a B-raf pseudogene are located on 7q in man

G. Sithanandam, T. Druck, L. A. Cannizzaro, G. Leuzzi, K. Huebner, U. R. Rapp

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Abstract

The B-raf gene was localized to human chromosome region 7p11-7qter by Southern blot analysis of its segregation in a panel of rodent-human hybrids, using a B-raf cDNA clone. Chromosomal in situ hybridization refined the localization to 7q33-36. Analysis of genomic B-raf clones identified a B-raf pseudogene in addition to the active gene. Based on the chromosomal mapping data we conclude that the pseudogene is located near the active gene.

Original languageEnglish (US)
Pages (from-to)795-799
Number of pages5
JournalOncogene
Volume7
Issue number4
Publication statusPublished - Jan 1 1992

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ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

Cite this

Sithanandam, G., Druck, T., Cannizzaro, L. A., Leuzzi, G., Huebner, K., & Rapp, U. R. (1992). B-raf and a B-raf pseudogene are located on 7q in man. Oncogene, 7(4), 795-799.