B-raf and a B-raf pseudogene are located on 7q in man

Gunamani Sithanandam, Teresa Druck, Linda A. Cannizzaro, Grace Leuzzi, Kay Huebner, Ulf R. Rapp

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

The B-raf gene was lozalized to human chromosome region 7p11-7qter by Southern blot analysis of its segregation in a panel of rodent-human hybrids, using a B-raf cDNA clone. Chromosomal in situ hybridization refined the localization to 7q33-36. Analysis of genomic B-raf clones identified a B-raf pseudogene in addition to the active gene. Based on the chromosomal mapping data we conclude that the pseudogene is located near the active gene.

Original languageEnglish (US)
Pages (from-to)795-799
Number of pages5
JournalOncogene
Volume7
Issue number4
StatePublished - Apr 1992
Externally publishedYes

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Pseudogenes
Clone Cells
Genes
Human Chromosomes
Southern Blotting
In Situ Hybridization
Rodentia
Complementary DNA

ASJC Scopus subject areas

  • Molecular Biology
  • Cancer Research
  • Genetics

Cite this

Sithanandam, G., Druck, T., Cannizzaro, L. A., Leuzzi, G., Huebner, K., & Rapp, U. R. (1992). B-raf and a B-raf pseudogene are located on 7q in man. Oncogene, 7(4), 795-799.

B-raf and a B-raf pseudogene are located on 7q in man. / Sithanandam, Gunamani; Druck, Teresa; Cannizzaro, Linda A.; Leuzzi, Grace; Huebner, Kay; Rapp, Ulf R.

In: Oncogene, Vol. 7, No. 4, 04.1992, p. 795-799.

Research output: Contribution to journalArticle

Sithanandam, G, Druck, T, Cannizzaro, LA, Leuzzi, G, Huebner, K & Rapp, UR 1992, 'B-raf and a B-raf pseudogene are located on 7q in man', Oncogene, vol. 7, no. 4, pp. 795-799.
Sithanandam G, Druck T, Cannizzaro LA, Leuzzi G, Huebner K, Rapp UR. B-raf and a B-raf pseudogene are located on 7q in man. Oncogene. 1992 Apr;7(4):795-799.
Sithanandam, Gunamani ; Druck, Teresa ; Cannizzaro, Linda A. ; Leuzzi, Grace ; Huebner, Kay ; Rapp, Ulf R. / B-raf and a B-raf pseudogene are located on 7q in man. In: Oncogene. 1992 ; Vol. 7, No. 4. pp. 795-799.
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