B-raf and a B-raf pseudogene are located on 7q in man

Gunamani Sithanandam, Teresa Druck, Linda A. Cannizzaro, Grace Leuzzi, Kay Huebner, Ulf R. Rapp

Research output: Contribution to journalArticlepeer-review

51 Scopus citations

Abstract

The B-raf gene was lozalized to human chromosome region 7p11-7qter by Southern blot analysis of its segregation in a panel of rodent-human hybrids, using a B-raf cDNA clone. Chromosomal in situ hybridization refined the localization to 7q33-36. Analysis of genomic B-raf clones identified a B-raf pseudogene in addition to the active gene. Based on the chromosomal mapping data we conclude that the pseudogene is located near the active gene.

Original languageEnglish (US)
Pages (from-to)795-799
Number of pages5
JournalOncogene
Volume7
Issue number4
StatePublished - Apr 1992
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

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