B cells at the molecular level

The biology of the B cell at the molecular level is being dissected at increasingly high definition. A recent international meeting^{{black star}} {black star} The meeting, The Molecular Basis of the Immune Response, was held in New York on 11-13 January 1988. included contributions that concentrated on, among other aspects, in-vitro B-cell differentiation, genetic recombination prior to immunoglobulin expression, V region gene usage and transcriptional control of V region gene expression, and control of immunoglobulin class switching.