Azidothymidine(AZT)‐induced siderosis

Simeon Pollack, Janet Weaver

Research output: Contribution to journalArticle

14 Scopus citations


Azidothymidine(AZT) interferes with heme synthesis. This should upregulate the synthesis of transferrin receptors and increase the amount of iron taken up by the cell. We found a 50% increase in the iron content of liver and a 20% increase in the iron content of macrophages in AZT‐treated mice.

Original languageEnglish (US)
Pages (from-to)230-233
Number of pages4
JournalAmerican Journal of Hematology
Issue number3
StatePublished - Jul 1993


  • AIDS
  • iron
  • liver
  • macrophage

ASJC Scopus subject areas

  • Hematology

Fingerprint Dive into the research topics of 'Azidothymidine(AZT)‐induced siderosis'. Together they form a unique fingerprint.

  • Cite this