Azidothymidine(AZT) interferes with heme synthesis. This should upregulate the synthesis of transferrin receptors and increase the amount of iron taken up by the cell. We found a 50% increase in the iron content of liver and a 20% increase in the iron content of macrophages in AZT‐treated mice.
|Original language||English (US)|
|Number of pages||4|
|Journal||American Journal of Hematology|
|State||Published - Jul 1993|
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