@article{aebb77fa2da6440a94544d4a72505685,
title = "Autophagy and primary cilia: Dual interplay",
abstract = "Primary cilia are microtubule-based organelles for sensing of the extracellular milieu and transducing this information into the cell through a variety of molecular signaling pathways. Functioning of the primary cilium has been recently connected to autophagy, a pathway for degradation of cellular components in lysosomes. Autophagy regulates the length of the cilia by removing proteins required for ciliogenesis, a phenomenon that is molecularly different if performed by basal autophagy or when autophagy is induced in response to various stressors. Here we review the current knowledge about the dual interaction between autophagy and ciliogenesis, and discuss the potential role that deregulated ciliary autophagy could have in pathologies with alterations in autophagy and ciliogenesis.",
author = "Olatz Pampliega and Cuervo, {Ana Maria}",
note = "Funding Information: Research in our groups is supported by grants from Initiative of Excellence of the University of Bordeaux and the Ligue Europ{\'e}enne Contre la Maladie d{\textquoteright}Alzheimer (OP) and the National Institutes of Health National Institute on Aging (AMC) and awards from The Rainwaters Foundation and The Beatrice and Roy Backus Foundation and a generous gift from Robert and Renee Belfer. Funding Information: Research in our groups is supported by grants from Initiative of Excellence of the University of Bordeaux and the Ligue Europ{\'e}enne Contre la Maladie d{\textquoteright}Alzheimer (OP) and the National Institutes of Health National Institute on Aging (AMC) and awards from The Rainwaters Foundation and The Beatrice and Roy Backus Foundation and a generous gift from Robert and Renee Belfer.",
year = "2016",
month = apr,
day = "1",
doi = "10.1016/j.ceb.2016.01.008",
language = "English (US)",
volume = "39",
pages = "1--7",
journal = "Current Opinion in Cell Biology",
issn = "0955-0674",
publisher = "Elsevier Limited",
}