Auditory-somatosensory multisensory processing in auditory association cortex: An fMRI study

John J. Foxe, Glenn R. Wylie, Antigona Martinez, Charles E. Schroeder, Daniel C. Javitt, David Guilfoyle, Walter Ritter, Micah M. Murray

Research output: Contribution to journalArticle

269 Citations (Scopus)

Abstract

Using high-field (3 Tesla) functional magnetic resonance imaging (fMRI), we demonstrate that auditory and somatosensory inputs converge in a subregion of human auditory cortex along the superior temporal gyrus. Further, simultaneous stimulation in both sensory modalities resulted in activity exceeding that predicted by summing the responses to the unisensory inputs, thereby showing multisensory integration in this convergence region. Recently, intracranial recordings in macaque monkeys have shown similar auditory-somatosensory convergence in a subregion of auditory cortex directly caudomedial to primary auditory cortex (area CM). The multisensory region identified in the present investigation may be the human homologue of CM. Our finding of auditory-somatosensory convergence in early auditory cortices contributes to mounting evidence for multisensory integration early in the cortical processing hierarchy, in brain regions that were previously assumed to be unisensory.

Original languageEnglish (US)
Pages (from-to)540-543
Number of pages4
JournalJournal of Neurophysiology
Volume88
Issue number1
StatePublished - 2002

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Auditory Cortex
Magnetic Resonance Imaging
Macaca
Temporal Lobe
Haplorhini
Brain

ASJC Scopus subject areas

  • Physiology
  • Neuroscience(all)

Cite this

Foxe, J. J., Wylie, G. R., Martinez, A., Schroeder, C. E., Javitt, D. C., Guilfoyle, D., ... Murray, M. M. (2002). Auditory-somatosensory multisensory processing in auditory association cortex: An fMRI study. Journal of Neurophysiology, 88(1), 540-543.

Auditory-somatosensory multisensory processing in auditory association cortex : An fMRI study. / Foxe, John J.; Wylie, Glenn R.; Martinez, Antigona; Schroeder, Charles E.; Javitt, Daniel C.; Guilfoyle, David; Ritter, Walter; Murray, Micah M.

In: Journal of Neurophysiology, Vol. 88, No. 1, 2002, p. 540-543.

Research output: Contribution to journalArticle

Foxe, JJ, Wylie, GR, Martinez, A, Schroeder, CE, Javitt, DC, Guilfoyle, D, Ritter, W & Murray, MM 2002, 'Auditory-somatosensory multisensory processing in auditory association cortex: An fMRI study', Journal of Neurophysiology, vol. 88, no. 1, pp. 540-543.
Foxe JJ, Wylie GR, Martinez A, Schroeder CE, Javitt DC, Guilfoyle D et al. Auditory-somatosensory multisensory processing in auditory association cortex: An fMRI study. Journal of Neurophysiology. 2002;88(1):540-543.
Foxe, John J. ; Wylie, Glenn R. ; Martinez, Antigona ; Schroeder, Charles E. ; Javitt, Daniel C. ; Guilfoyle, David ; Ritter, Walter ; Murray, Micah M. / Auditory-somatosensory multisensory processing in auditory association cortex : An fMRI study. In: Journal of Neurophysiology. 2002 ; Vol. 88, No. 1. pp. 540-543.
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