Attraction of human monocytes by the neuropeptide secretoneurin

Norbert Reinisch; Rudolf Kirchmair; Christian M. Kähler; Ruth Hogue-Angeletti; Reiner Fischer-Colbrie; Hans Winkler; Christian J. Wiedermann

doi:10.1016/0014-5793(93)81676-Q

Attraction of human monocytes by the neuropeptide secretoneurin

Norbert Reinisch, Rudolf Kirchmair, Christian M. Kähler, Ruth Hogue-Angeletti, Reiner Fischer-Colbrie, Hans Winkler, Christian J. Wiedermann

Developmental & Molecular Biology

Research output: Contribution to journal › Article › peer-review

108 Scopus citations

Abstract

Secretoneurin is a newly discovered 33-amino-acid peptide derived from secretogranin II (chromogranin C) that is found in sensory afferent C-fibers. We show here that secretoneurin triggers the selective migration of human monocytes in vitro and in vivo. Combinations of secretoneurin with the sensory neuropeptides, substance P or somatostatin, synergistically stimulate such migration. The attraction of monocytes represents the first established function of secretoneurin as a sensory neuropeptide.

Original language	English (US)
Pages (from-to)	41-44
Number of pages	4
Journal	FEBS Letters
Volume	334
Issue number	1
DOIs	https://doi.org/10.1016/0014-5793(93)81676-Q
State	Published - Nov 8 1993

Keywords

Chemotaxis
Monocyte
Neurogenic inflammation
Secretogranin II
Secretoneurin

ASJC Scopus subject areas

Biophysics
Structural Biology
Biochemistry
Molecular Biology
Genetics
Cell Biology

Access to Document

10.1016/0014-5793(93)81676-Q

Fingerprint Dive into the research topics of 'Attraction of human monocytes by the neuropeptide secretoneurin'. Together they form a unique fingerprint.

Cite this

@article{ce5e532eb00f439f978861488340a064,

title = "Attraction of human monocytes by the neuropeptide secretoneurin",

abstract = "Secretoneurin is a newly discovered 33-amino-acid peptide derived from secretogranin II (chromogranin C) that is found in sensory afferent C-fibers. We show here that secretoneurin triggers the selective migration of human monocytes in vitro and in vivo. Combinations of secretoneurin with the sensory neuropeptides, substance P or somatostatin, synergistically stimulate such migration. The attraction of monocytes represents the first established function of secretoneurin as a sensory neuropeptide.",

keywords = "Chemotaxis, Monocyte, Neurogenic inflammation, Secretogranin II, Secretoneurin",

author = "Norbert Reinisch and Rudolf Kirchmair and K{\"a}hler, {Christian M.} and Ruth Hogue-Angeletti and Reiner Fischer-Colbrie and Hans Winkler and Wiedermann, {Christian J.}",

year = "1993",

month = nov,

day = "8",

doi = "10.1016/0014-5793(93)81676-Q",

language = "English (US)",

volume = "334",

pages = "41--44",

journal = "FEBS Letters",

issn = "0014-5793",

publisher = "Elsevier",

number = "1",

}

TY - JOUR

T1 - Attraction of human monocytes by the neuropeptide secretoneurin

AU - Reinisch, Norbert

AU - Kirchmair, Rudolf

AU - Kähler, Christian M.

AU - Hogue-Angeletti, Ruth

AU - Fischer-Colbrie, Reiner

AU - Winkler, Hans

AU - Wiedermann, Christian J.

PY - 1993/11/8

Y1 - 1993/11/8

N2 - Secretoneurin is a newly discovered 33-amino-acid peptide derived from secretogranin II (chromogranin C) that is found in sensory afferent C-fibers. We show here that secretoneurin triggers the selective migration of human monocytes in vitro and in vivo. Combinations of secretoneurin with the sensory neuropeptides, substance P or somatostatin, synergistically stimulate such migration. The attraction of monocytes represents the first established function of secretoneurin as a sensory neuropeptide.

AB - Secretoneurin is a newly discovered 33-amino-acid peptide derived from secretogranin II (chromogranin C) that is found in sensory afferent C-fibers. We show here that secretoneurin triggers the selective migration of human monocytes in vitro and in vivo. Combinations of secretoneurin with the sensory neuropeptides, substance P or somatostatin, synergistically stimulate such migration. The attraction of monocytes represents the first established function of secretoneurin as a sensory neuropeptide.

KW - Chemotaxis

KW - Monocyte

KW - Neurogenic inflammation

KW - Secretogranin II

KW - Secretoneurin

UR - http://www.scopus.com/inward/record.url?scp=0027383931&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027383931&partnerID=8YFLogxK

U2 - 10.1016/0014-5793(93)81676-Q

DO - 10.1016/0014-5793(93)81676-Q

M3 - Article

C2 - 8224224

AN - SCOPUS:0027383931

VL - 334

SP - 41

EP - 44

JO - FEBS Letters

JF - FEBS Letters

SN - 0014-5793

IS - 1

ER -